Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646688 | 0.93 | TSHR (0.71) | KMT2AMEN1TSHRGRIN1GRIN2A | |
| SCHEMBL7807178 | 0.87 | MEN1 (0.55) | KMT2AMEN1TSHRGRIN1GRIN2A | |
| SCHEMBL16566321 | 0.81 | GRIN1 (0.62) | KMT2AMEN1TSHRGRIN1GRIN2A | |
| SCHEMBL7467608 | 0.80 | AKR1C1 (0.59) | KMT2AMEN1TSHRAKR1C1 | |
| SCHEMBL7810973 | 0.80 | AKR1C1 (0.55) | KMT2AAKR1C1SMPD1 | |
| SCHEMBL8587542 | 0.79 | AKR1C1 (0.57) | KMT2AMEN1TSHRAKR1C1 | |
| SCHEMBL2636679 | 0.79 | KMT2A (0.88) | KMT2AMEN1TSHRPLA2G4B | |
| SCHEMBL521247 | 0.77 | AKR1C1 (0.54) | KMT2AMEN1TSHRAKR1C1 | |
| SCHEMBL23163974 | 0.77 | ADAM17 (0.53) | KMT2AMEN1TSHRAKR1C1NR1H4 | |
| SCHEMBL29705586 | 0.74 | KMT2A (0.47) | KMT2AMEN1TSHRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| CN-101304993-A | Compounds and compositions as ppar modulators | IRM LLC (BM) | 2008-11-12 | — | — | CN | disclosed |
| EP-1945633-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056497-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056497-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | KMT2A 3705/4885MEN1 4844/4885TSHR 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.