Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606853 | 0.87 | KMT2A (0.73) | MEN1KMT2AGRIN1GRIN2AGRIN2B | |
| SCHEMBL30683829 | 0.83 | ADAM17 (0.53) | MEN1KMT2ATSHRALDH1A1ADAM17 | |
| SCHEMBL2846322 | 0.83 | ADAM17 (0.53) | MEN1KMT2ATSHRALDH1A1ADAM17 | |
| SCHEMBL2846350 | 0.81 | ADAM17 (0.60) | SMPD1CYP2D6ADAM17 | |
| SCHEMBL8585754 | 0.81 | ADAM17 (0.52) | MEN1KMT2ATSHRALDH1A1ADAM17 | |
| SCHEMBL11646688 | 0.81 | TSHR (0.71) | MEN1KMT2AGRIN1GRIN2AGRIN2B | |
| SCHEMBL23163761 | 0.80 | ADAM17 (0.64) | ADAM17 | |
| SCHEMBL8357656 | 0.79 | ADAM17 (0.64) | ADAM17NR1H4 | |
| SCHEMBL16566321 | 0.79 | GRIN1 (0.62) | MEN1KMT2AGRIN1GRIN2AGRIN2B | |
| SCHEMBL27736564 | 0.77 | ADAM17 (0.56) | MEN1KMT2AALDH1A1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |