Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825851 | 0.98 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL27542155 | 0.93 | MAPT (0.59) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL544942 | 0.91 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL2222140 | 0.91 | HDAC1 (0.67) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL23069543 | 0.89 | TDP1 (0.61) | HDAC3HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL17223648 | 0.89 | HDAC1 (0.64) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL406382 | 0.88 | ALOX5 (0.59) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL8790951 | 0.88 | MAPT (0.56) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7431738 | 0.87 | TDP1 (0.63) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL13498527 | 0.87 | MAPT (0.63) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433964-B | Electrolyte solution, electrochemical device, lithium ion secondary battery, and assembly | 大金工业株式会社 | 2023-02-17 | — | — | CN | disclosed |
| WO-2016009630-A1 | METHOD FOR PRODUCING ALGA FAT OR OIL AND ALGA FAT OR OIL PRODUCTION PROMOTER | 国立研究開発法人科学技術振興機構 | 2016-01-21 | — | — | WO | disclosed |
| EP-1390491-B1 | METHOD FOR TREATING NEURODEGENERATIVE, PSYCHIATRIC AND OTHER DISORDERS WITH DEACETYLASE INHIBITORS | UNIV CALIFORNIA (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-0672648-B1 | Threo (2R,3S)-3-amino-2-hydroxypentanoic acid and threo (2R,3S)-3-(p-methoxy-benzyloxycarbonyl/FMOC) amino-2-hydroxy-pentanoic acid | ZAIDAN HOJIN BISEIBUTSU (JP) | 1998-09-23 | — | — | EP | disclosed |
| EP-0672648-A1 | Threo-3-amino-2-hydroxypentanoic acid and threo (2R,3S), (2S,3R)-3-(p-methoxy-benzyloxycarbonyl) amino-2-hydroxy-pentanoic acid | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5359138-A | Endopeptidase inhibitors for treatment of amnesia and autoimmune diseases | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5162500-A | POSTSTATIN AND RELATED COMPOUNDS OR SALTS THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0423358-A1 | POSTOSTATIN AND RELATED COMPOUND THEREOF, OR THEIR SALTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4006009-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4004912-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |