Ethyl Fumarate

Ethyl Fumarate

SCHEMBL460704

C=C.C=CCOC(=O)C=C.CCOC(=O)C=CC(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.65
MAPT P10636 2/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
TSHR P16473 7/20 0.40
HPGD P15428 1/20 0.40
APP P05067 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 1/20 0.35
TP53 P04637 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Fumarate SCHEMBL27854702 1.00 HCAR2 (0.65) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL2359268 0.90 MAPT (0.55) HCAR2MAPTCACNA1BAPBA1TSHR
Ethyl Fumarate SCHEMBL1067038 0.90 HCAR2 (0.80) HCAR2MAPTTSHRHPGDALDH1A1
SCHEMBL2359270 0.90 MAPT (0.55) HCAR2MAPTCACNA1BAPBA1TSHR
Diethyl Maleate SCHEMBL20293748 0.86 HCAR2 (0.59) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL4453032 0.86 HCAR2 (0.59) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL4453038 0.86 HCAR2 (0.59) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL7081971 0.86 HCAR2 (0.59) HCAR2MAPTCACNA1BAPBA1TSHR
Maleic Acid SCHEMBL8772268 0.86 HCAR2 (0.72) HCAR2MAPTTSHRHPGDALDH1A1
Fumaric Acid SCHEMBL8925070 0.86 HCAR2 (0.72) HCAR2MAPTTSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20170174950-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-06-22 US disclosed
US-9631054-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2017-04-25 US disclosed
US-20110287243-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-24 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed