Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.35 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978382 | 0.83 | KLKB1 (0.38) | PTGS1PTGS2TRPV1PIK3CAMTOR | |
| SCHEMBL4608994 | 0.80 | CA12 (0.39) | — | |
| SCHEMBL4624222 | 0.80 | PTGS2 (0.34) | PTGS1PTGS2CRACR2APIK3CAMTOR | |
| SCHEMBL12871652 | 0.77 | PTGS1 (0.58) | PTGS1PTGS2TRPV1 | |
| SCHEMBL12871665 | 0.76 | PTGS2 (0.51) | PTGS1PTGS2TRPV1 | |
| SCHEMBL12871769 | 0.74 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL31546283 | 0.73 | AR (0.40) | PTGS1PTGS2TRPV1CRACR2A | |
| SCHEMBL31546278 | 0.72 | PTGS2 (0.50) | PTGS1PTGS2TRPV1 | |
| SCHEMBL19954647 | 0.72 | TRPV1 (0.41) | PTGS1PTGS2TRPV1PIK3CAMTOR | |
| SCHEMBL4608788 | 0.71 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |