Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 5/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978374 | 0.78 | NPC1 (0.38) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL28416920 | 0.78 | NPC1 (0.40) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL28422115 | 0.78 | NPC1 (0.38) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL16202042 | 0.78 | MAPT (0.52) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL695186 | 0.77 | NPC1 (0.50) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL5956069 | 0.77 | NPC1 (0.49) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL4429679 | 0.76 | PRMT6 (0.43) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL25015829 | 0.75 | NPC1 (0.50) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL8259527 | 0.74 | NPC1 (0.58) | NPC1MAPTPRMT6RAB9ANPSR1 | |
| SCHEMBL15985680 | 0.73 | NPC1 (0.48) | NPC1MAPTPRMT6RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |