SCHEMBL460729

SCHEMBL460729

O=C=NCc1ccc(Cl)c(CN=C=O)c1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TAAR1 Q96RJ0 1/20 0.33
PYCR1 P32322 1/20 0.33
MIF P14174 1/20 0.33
IDO1 P14902 1/20 0.31
TSHR P16473 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387410 1.00 MAPK1 (0.36) MAPK1TDP1TAAR1PYCR1MIF
SCHEMBL30387398 0.85 MAPK1 (0.47) MAPK1TDP1TAAR1PYCR1IDO1
SCHEMBL139341 0.85 MAPK1 (0.47) MAPK1TDP1TAAR1PYCR1IDO1
SCHEMBL11716213 0.82 MIF (0.36) MIFTSHRCYP3A4
SCHEMBL14465785 0.81 S1PR1 (0.37) MAPK1TDP1TAAR1PYCR1TSHR
SCHEMBL31522190 0.80 CYP3A4 (0.33) MIFTSHRCYP3A4
SCHEMBL29170709 0.80 MAPK1 (0.36) MAPK1TDP1TAAR1MIF
SCHEMBL10929233 0.80 MAPK1 (0.34) MAPK1TDP1
SCHEMBL460468 0.79 CYP3A4 (0.35) MIFTSHRCYP3A4
SCHEMBL29387408 0.79 CYP3A4 (0.35) MIFTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4775733-A POLYTHIOURETHANES MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-10-04 US claimed
EP-4731688-A1 METHOD FOR THE PRODUCTION OF A HYDROXYL-GROUP TERMINATED OXAZOLIDINONE COMPOSITION Covestro Deutschland AG (DE) 2026-04-29 EP disclosed
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-4640732-A1 ONE-COMPONENT SYSTEM FOR COATINGS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4640731-A1 ONE-COMPONENT COATING COMPOSITION FOR FOOD CONTAINERS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4357382-B1 IONICALLY MODIFIED POLYISOCYANATE MIXTURE COVESTRO DEUTSCHLAND AG (DE) 2025-07-23 EP disclosed
EP-4574864-A1 POLYISOCYANATE MIXTURE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
EP-4574860-A1 USE OF A SOLVENT-FREE COMPOSITION COMPRISING EPOXY-FUNCTIONAL OXAZOLIDINONES FOR PRODUCING ADHESIVES, SEALING COMPOUNDS, POTTING COMPOUNDS, COMPOSITES, SUCH AS FIBER COMPOSITE MATERIALS, OR MOLDINGS, OR FOR PRODUCING COATINGS ON MINERAL, METALLIC OR PLASTIC SUBSTRATES, AND THE PRODUCTS THUS OBTAINED Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
EP-4574870-A1 BLOCKED POLYISOCYANATE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
US-5756766-A Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1998-05-26 US disclosed
US-5652321-A Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-29 US disclosed
EP-0713105-A2 Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-05-22 EP disclosed
EP-0390218-B1 Anti-reflection optical element HOYA CORP (JP) 1995-08-09 EP disclosed
US-5306799-A High refractive index plastic lens and composition therefor MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
US-5181141-A Good mechanical and chemical properties HOYA CORPORATION (JP) 1993-01-19 US disclosed
EP-0390218-A2 Anti-reflection optical element HOYA CORPORATION (JP) 1990-10-03 EP disclosed
EP-0235743-B1 HIGH-REFRACTIVITY PLASTIC LENS RESIN MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-31 EP disclosed
US-4775733-A POLYTHIOURETHANES MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-10-04 US disclosed
EP-0235743-A1 High-refractivity plastic lens resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 MAPK1 3457/4885TDP1 4236/4885TAAR1 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.