Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531870 | 0.85 | NPC1 (0.78) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10245542 | 0.84 | NPC1 (1.00) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9029579 | 0.82 | NPC1 (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2837185 | 0.82 | RAB9A (0.73) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29006444 | 0.82 | NPC1 (0.73) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28372775 | 0.82 | NPC1 (0.73) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30362152 | 0.82 | NPC1 (0.73) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14541545 | 0.81 | NPC1 (0.68) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16636349 | 0.81 | NPC1 (0.68) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4464247 | 0.81 | NPC1 (0.68) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | disclosed |
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
| US-4824843-A | Substituted amide inhibitors of cholesterol absorption | WARNER-LAMBERT COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | CCR3, CCR1, CCR4 | RAB9A 2140/4885NPC1 848/4885ALDH1A1 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.