Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 10/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604016 | 0.88 | CXCR4 (0.49) | CXCR4TAAR1PYGLNAMPTALDH1A1 | |
| SCHEMBL4607724 | 0.88 | CXCR4 (0.47) | CXCR4KDM4ENAMPTALDH1A1 | |
| SCHEMBL4605688 | 0.85 | CXCR4 (0.47) | CXCR4TAAR1NAMPTALDH1A1 | |
| SCHEMBL4605105 | 0.85 | CXCR4 (0.45) | CXCR4TAAR1NAMPTALDH1A1 | |
| SCHEMBL4589207 | 0.84 | CXCR4 (0.56) | CXCR4NAMPTALDH1A1 | |
| SCHEMBL4589896 | 0.81 | CXCR4 (0.48) | CXCR4TAAR1NAMPTALDH1A1 | |
| SCHEMBL1802205 | 0.80 | CXCR4 (0.49) | CXCR4KDM4ENAMPTALDH1A1ALOX15 | |
| SCHEMBL1793373 | 0.78 | CXCR4 (0.47) | CXCR4NAMPTALDH1A1 | |
| SCHEMBL1794515 | 0.78 | CXCR4 (0.49) | CXCR4ALDH1A1 | |
| SCHEMBL1798048 | 0.76 | CXCR4 (0.55) | CXCR4TAAR1NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822459-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-1790639-B1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20080009495-A1 | Compound Containing Basic Group and Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009495-A1 | Compound Containing Basic Group and Use Thereof | CXCR4, CCR5, CXCR3 | CXCR4 1/4885KDM4E 4354/4885TAAR1 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.