SCHEMBL4607651

SCHEMBL4607651

O=C(O)CNC(=O)N1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
EPHX2 P34913 1/20 0.46
RBP4 P02753 1/20 0.45
ALDH1A1 P00352 2/20 0.43
HTT P42858 3/20 0.41
GAA P10253 1/20 0.39
ATM Q13315 1/20 0.38
MME P08473 1/20 0.37
HSD11B1 P28845 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7338141 0.98 KMT2A (0.45) KMT2AEPHX2RBP4ALDH1A1HTT
SCHEMBL24664607 0.95 KMT2A (0.46) KMT2AEPHX2RBP4ALDH1A1HTT
SCHEMBL7804748 0.81 KMT2A (0.50) KMT2AEPHX2ALDH1A1HTTATM
SCHEMBL6444661 0.81 HTT (0.63) KMT2ARBP4HTTGAAMAPT
SCHEMBL4412731 0.81 KMT2A (0.52) KMT2AEPHX2RBP4ALDH1A1HTT
SCHEMBL8135298 0.80 USP5 (0.48) KMT2AALDH1A1POLB
SCHEMBL14941550 0.79 KMT2A (0.48) KMT2AEPHX2ALDH1A1HTTGAA
SCHEMBL8382720 0.78 KMT2A (0.48) KMT2ARBP4HTTPOLB
SCHEMBL14032638 0.78 ALDH1A1 (0.49) KMT2ARBP4ALDH1A1GAAPOLB
SCHEMBL30967266 0.77 HTT (0.41) KMT2AEPHX2ALDH1A1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP disclosed
WO-2024215876-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS PROTOMER TECHNOLOGIES, INC. (US) 2024-10-17 WO disclosed
EP-1874739-A1 PHARMACEUTICALLY ACTIVE DIAZEPANES Novartis AG (CH) 2008-01-09 EP disclosed
WO-2006111371-A1 PHARMACEUTICALLY ACTIVE DIAZEPANES NOVARTIS AG (CH) 2006-10-26 WO disclosed