Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459393 | 0.83 | DRD2 (0.60) | DRD2DRD3SMYD3 | |
| SCHEMBL8434564 | 0.83 | DRD2 (0.60) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL12505562 | 0.81 | DRD2 (0.58) | DRD2DRD3SMYD3 | |
| Hydrochloric Acid SCHEMBL355061 | 0.81 | DRD2 (0.58) | DRD2DRD3SMYD3 | |
| SCHEMBL10247342 | 0.81 | DRD2 (0.57) | DRD2DRD3 | |
| SCHEMBL10247424 | 0.81 | DRD2 (0.57) | DRD2DRD3 | |
| SCHEMBL355227 | 0.81 | DRD2 (0.57) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL353594 | 0.79 | DRD2 (0.56) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL354592 | 0.79 | DRD2 (0.56) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL354608 | 0.79 | DRD2 (0.56) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031993-A1 | NOVEL N-HYDROXY-BENZAMIDES FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |