Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12505562 | 0.98 | DRD2 (0.58) | DRD2DRD3ALDH1A1ACHEMAPT | |
| Hydrochloric Acid SCHEMBL355061 | 0.98 | DRD2 (0.58) | DRD2DRD3ALDH1A1ACHEMAPT | |
| SCHEMBL355303 | 0.93 | OPRK1 (0.60) | DRD2DRD3ALDH1A1MAPTNFKB1 | |
| SCHEMBL355302 | 0.93 | OPRK1 (0.60) | DRD2DRD3ALDH1A1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL4780269 | 0.92 | OPRK1 (0.58) | DRD2DRD3ALDH1A1MAPTNFKB1 | |
| SCHEMBL8434564 | 0.87 | DRD2 (0.60) | DRD2DRD3ALDH1A1ACHEMAPT | |
| Hydrochloric Acid SCHEMBL6642375 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EKDM1ASMYD3 | |
| SCHEMBL460777 | 0.83 | HDAC8 (0.59) | DRD2DRD3SMYD3 | |
| SCHEMBL10247342 | 0.81 | DRD2 (0.57) | DRD2DRD3ALDH1A1ACHEMAPT | |
| SCHEMBL355227 | 0.81 | DRD2 (0.57) | DRD2DRD3ALDH1A1ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |