Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.95 |
| ▸ | GAA | P10253 | 10/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.95 |
| ▸ | MEN1 | O00255 | 6/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.95 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | APP | P05067 | 1/20 | 0.72 |
| ▸ | SNCA | P37840 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388147 | 0.98 | MAPT (1.00) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL217480 | 0.98 | MAPT (1.00) | MAPTGAAALDH1A1KDM4EMEN1 | |
| Methane SCHEMBL4054340 | 0.95 | MAPT (0.95) | MAPTGAAALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29809096 | 0.95 | MAPT (0.95) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL9396738 | 0.93 | MAPT (0.91) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL9396742 | 0.93 | MAPT (0.91) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL4607773 | 0.90 | MAPT (0.86) | MAPTGAAALDH1A1KDM4EMEN1 | |
| Sulfuric Acid SCHEMBL9190448 | 0.86 | MAPT (0.77) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL28901135 | 0.86 | MAPT (0.77) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL5945616 | 0.85 | MAPT (0.76) | MAPTGAAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185501-B1 | PREPARATION OF SUBSTITUTED AROMATIC AMINES | UNIROYAL CHEM CO INC (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1185501-A1 | PREPARATION OF SUBSTITUTED AROMATIC AMINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076952-A1 | PREPARATION OF SUBSTITUTED AROMATIC AMINES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6069279-A | AROMATIC AMINE SUCH AS ANILINE IS OXIDIZED WITH OXYGEN OR HYDROGEN PEROXIDE IN THE PRESENCE OF A METAL PENTACYANO FERRATE(II) COMPLEX, WITH SUBSEQUENT CATALYTIC REDUCTION OF THE COMPLEX BY HYDROGENATION IN THE PRESENCE OF METAL CATALYST | ADDIVANT USA, LLC | 2000-05-30 | — | — | US | disclosed |