Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 13/20 | 0.38 |
| ▸ | RAMP1 | O60894 | 8/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CALCA | P06881 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139099 | 0.86 | MAPK1 (0.47) | MAPK1DPP4 | |
| SCHEMBL14139102 | 0.84 | MAPK1 (0.45) | MAPK1CALCRLRAMP1PARP1ALDH1A1 | |
| SCHEMBL3954158 | 0.82 | ALOX15 (0.47) | MAPK1CALCRLPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4608265 | 0.81 | CHRM4 (0.55) | CALCRLRAMP1CALCACHRM4 | |
| SCHEMBL14141304 | 0.77 | CRBN (0.44) | MAPK1CALCRLPARP1 | |
| SCHEMBL14139186 | 0.77 | MAPK1 (0.47) | MAPK1CALCRLPARP1CALCACHRM4 | |
| SCHEMBL6657476 | 0.77 | MAPK1 (0.52) | MAPK1CALCRLPARP1 | |
| SCHEMBL14498279 | 0.76 | PARP1 (0.50) | MAPK1CALCRLPARP1 | |
| SCHEMBL14139100 | 0.76 | MAPK1 (0.44) | MAPK1CALCRLPARP1SMN1; SMN2CHRM4 | |
| SCHEMBL14139101 | 0.75 | MAPK1 (0.47) | MAPK1CALCRLRAMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0927192-B1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-12 | — | — | EP | disclosed |