Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609111 | 1.00 | HRH3 (0.48) | HRH3 | |
| SCHEMBL14538713 | 1.00 | HRH3 (0.48) | HRH3 | |
| SCHEMBL4624618 | 1.00 | HRH3 (0.48) | HRH3 | |
| SCHEMBL4624657 | 0.95 | HRH3 (0.48) | HRH3 | |
| SCHEMBL4624649 | 0.95 | HRH3 (0.48) | HRH3 | |
| SCHEMBL4653089 | 0.92 | NPY1R (0.47) | HRH3 | |
| SCHEMBL4653085 | 0.92 | NPY1R (0.47) | HRH3 | |
| SCHEMBL4653088 | 0.92 | NPY1R (0.47) | HRH3 | |
| SCHEMBL4608914 | 0.86 | SLC6A3 (0.47) | HRH3 | |
| SCHEMBL4651854 | 0.84 | NPY1R (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948605-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007061741-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | disclosed |