Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.84 |
| ▸ | ESR1 | P03372 | 17/20 | 0.83 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | PLD2 | O14939 | 1/20 | 0.83 |
| ▸ | KDM1A | O60341 | 1/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.83 |
| ▸ | USP2 | O75604 | 1/20 | 0.83 |
| ▸ | C5 | P01031 | 1/20 | 0.83 |
| ▸ | FYN | P06241 | 1/20 | 0.83 |
| ▸ | PGR | P06401 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827879 | 0.94 | ENPP3 (0.87) | STSESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL1439001 | 0.94 | ENPP3 (0.87) | STSESR1ESR2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1438899 | 0.93 | ENPP3 (0.85) | STSESR1ESR2MEN1ALDH1A1 | |
| Raloxifene SCHEMBL2733917 | 0.93 | ESR1 (0.90) | STSESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL10827744 | 0.93 | ENPP3 (0.85) | STSESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL2234861 | 0.92 | STS (1.00) | STSESR1ESR2MEN1ALDH1A1 | |
| Raloxifene SCHEMBL1751808 | 0.91 | ESR1 (0.93) | STSESR1ESR2MEN1ALDH1A1 | |
| Raloxifene SCHEMBL3162158 | 0.91 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA | |
| Raloxifene SCHEMBL6144 | 0.91 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL5821250 | 0.91 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003116-A9 | PROCESS FOR PREPARING RALOXIFENE HYDROCHLORIDE | ERREGIERRE SPA (IT) | 2008-09-25 | — | — | WO | disclosed |
| EP-1641773-B1 | PROCESS FOR PREPARING RALOXIFENE HYDROCHLORIDE | ERREGIERRE SPA (IT) | 2008-07-23 | — | — | EP | disclosed |
| US-20070100147-A1 | Process for preparing raloxifene hydrochloride | ERREGIERRE S.P.A (IT) | 2007-05-03 | — | — | US | disclosed |
| EP-1641773-A1 | PROCESS FOR PREPARING RALOXIFENE HYDROCHLORIDE | ERREGIERRE S.p.A. (IT) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005003116-A1 | PROCESS FOR PREPARING RALOXIFENE HYDROCHLORIDE | ERREGIERRE S.P.A. (IT) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100147-A1 | Process for preparing raloxifene hydrochloride | KAT2A, ADH1A, KAT2B | STS 487/4885ESR1 78/4885ESR2 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.