SCHEMBL4608345

SCHEMBL4608345

CCCCc1ccc(CC[CH]c2ccc(C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 2/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SKP2 Q13309 1/20 0.40
IGF1R P08069 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5058134 0.89 CYP2A6 (0.48) CA2CA1ALDH1A1SMN1; SMN2IGF1R
SCHEMBL1611150 0.85 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1610419 0.85 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1610193 0.83 ALDH1A1 (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL168272 0.82 CA2 (0.56) CA2CA1CNR2ALDH1A1HSD17B10
P-Xylene SCHEMBL9064447 0.82 CA2 (0.56) CA2CA1CNR2ALDH1A1HSD17B10
SCHEMBL1611355 0.81 ESR1 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1610394 0.81 ESR1 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1610637 0.81 CA2 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1612718 0.81 CYP2A6 (0.46) CA1ALDH1A1HPGDSMN1; SMN2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727842-B1 METHOD FOR THE PRODUCTION OF POLYISOCYANATES COMPRISING ISOCYANURATE GROUPS AND USE THEREOF BASF SE (DE) 2008-12-17 EP disclosed
EP-1976797-A2 PHYLLOSILICATE FORMULATIONS FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES Bayer Technology Services GmbH (DE) 2008-10-08 EP disclosed
EP-1866045-A1 METHOD FOR THE DISTILLATIVE PURIFICATION OF SLOW-EVAPORATING FLUIDS Bayer Technology Services GmbH (DE) 2007-12-19 EP disclosed
WO-2007080117-A2 PHYLLOSILICATE FORMULATIONS FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES BAYER TECHNOLOGY SERVICES GMBH (DE) 2007-07-19 WO disclosed
EP-1711472-A1 MEHTOD FOR PRODUCING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2006-10-18 EP disclosed
WO-2006100023-A1 METHOD FOR THE DISTILLATIVE PURIFICATION OF SLOW-EVAPORATING FLUIDS BAYER TECHNOLOGY SERVICES GMBH (DE) 2006-09-28 WO disclosed
EP-1618165-A1 USE OF AN IONIC LIQUID BASF AKTIENGESELLSCHAFT (DE) 2006-01-25 EP disclosed
WO-2005070896-A1 MEHTOD FOR PRODUCING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 WO disclosed
WO-2004090066-A1 USE OF AN IONIC LIQUID BASF AKTIENGESELLSCHAFT (DE) 2004-10-21 WO disclosed