Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055513 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL915218 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL29674753 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL2889714 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1417856 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1711563 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL430516 | 0.82 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL23337668 | 0.81 | LMNA (0.50) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL13070538 | 0.81 | LMNA (0.50) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL27887380 | 0.79 | LMNA (0.59) | LMNAADRA2CKDM4EADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831769-B2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | LAVIN DR THOMAS N (US) | 2008-07-23 | — | — | EP | claimed |