SCHEMBL460869

SCHEMBL460869

Nc1cc(N)c(OCCO)cc1OCCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.48
USP2 O75604 2/20 0.48
CASP1 P29466 2/20 0.48
HSD17B10 Q99714 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
THRB P10828 1/20 0.48
G6PD P11413 1/20 0.48
ALOX15 P16050 1/20 0.48
PRSS1 P07477 8/20 0.41
LOX P28300 1/20 0.41
AOC3 Q16853 1/20 0.41
POLB P06746 2/20 0.38
TP53 P04637 2/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7167133 0.98 KDM4E (0.47) ALDH1A1KDM4EMEN1MAPTKMT2A
Hydrochloric Acid SCHEMBL1872731 0.98 KDM4E (0.47) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL13753698 0.93 PRSS1 (0.42) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8034582 0.90 GAA (0.47) ALDH1A1KDM4EMEN1MAPTKMT2A
Hydrochloric Acid SCHEMBL10891581 0.88 GAA (0.46) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL7985926 0.87 CASP1 (0.43) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL29353325 0.86 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL10889603 0.86 GAA (0.41) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL12000686 0.86 LOX (0.40) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL455549 0.86 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
EP-2274286-B1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF PROCTER & GAMBLE (US) 2015-08-05 EP claimed
EP-0634162-A1 Keratinous fibers dyeing composition containing a para-aminophenol, a meta-aminophenol and a metaphenylendiamine L'OREAL (FR) 1995-01-18 EP claimed
EP-0658093-A4 PROCESS AND KIT FOR DYEING HAIR. BRISTOL MYERS SQUIBB CO (US) 1994-09-23 EP claimed
EP-0605320-A1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same L'OREAL (FR) 1994-07-06 EP claimed
US-5279617-A Using melanin precursor; oxidizing dopa compound with a ferricyanide salt CLAIROL INCORPORATED (US) 1994-01-18 US claimed
US-5279618-A Forming melanin precursor by reacting dopa with hair dye CLAIROL INCORPORATED (US) 1994-01-18 US claimed
WO-1993010744-A2 PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR L'OREAL (FR) 1993-06-10 WO claimed
EP-0545257-A2 Oxidative hair coloring compositions and process for dyeing human keratinous fibers BRISTOL-MYERS SQUIBB COMPANY (US) 1993-06-09 EP claimed
EP-0544400-A2 P-Phenylenediamine substituted by a quaternary ammonium group and an electron withdrawing group Bristol-Myers Squibb Company (US) 1993-06-02 EP claimed
WO-1993005759-A1 PROCESS AND KIT FOR DYEING HAIR BRISTOL-MYERS SQUIBB COMPANY (US) 1993-04-01 WO claimed
US-5139532-A In a tinctorially effective hair dye developer also containing and an adjuvant selected from surfactans, alkalizing agents, thickeners, chealting agents and perfumes CLAIROL, INC. (US) 1992-08-18 US claimed