Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | IDH1 | O75874 | 8/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434312 | 0.82 | MAPT (0.43) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL4061700 | 0.76 | NPC1 (0.43) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL4608788 | 0.76 | NPC1 (0.45) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL25015829 | 0.75 | NPC1 (0.50) | PRMT6NPC1MAPTRAB9ANPSR1 | |
| SCHEMBL4624222 | 0.72 | PTGS2 (0.34) | MAPT | |
| SCHEMBL11983537 | 0.71 | PRMT6 (0.43) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL8259527 | 0.70 | NPC1 (0.58) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL9082652 | 0.70 | PRMT6 (0.49) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL16202042 | 0.68 | MAPT (0.52) | PRMT6NPC1MAPTIDH1IDH2 | |
| SCHEMBL13719485 | 0.68 | IDH1 (0.51) | PRMT6NPC1MAPTIDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |