Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670999 | 0.81 | SCN4A (0.41) | SCN4ATDP1CHRM2CHRM4CHRM5 | |
| Methane SCHEMBL28528438 | 0.79 | SCN4A (0.40) | SCN4ATDP1CHRM2CHRM4CHRM5 | |
| SCHEMBL51937 | 0.78 | RIPK1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2781356 | 0.75 | DPP4 (0.55) | SCN4A | |
| SCHEMBL2781359 | 0.75 | DPP4 (0.55) | SCN4A | |
| SCHEMBL2784864 | 0.75 | DPP4 (0.55) | SCN4A | |
| SCHEMBL7731055 | 0.73 | CYP19A1 (0.50) | MEN1KMT2A | |
| SCHEMBL11680802 | 0.73 | IDO1 (0.42) | SCN4ACHRM3 | |
| SCHEMBL4672036 | 0.71 | HRH1 (0.68) | SCN4A | |
| SCHEMBL4672537 | 0.71 | HRH1 (0.68) | SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113967258-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-25 | — | — | CN | disclosed |
| CN-113956325-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-21 | — | — | CN | disclosed |
| CN-113786495-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2021-12-14 | — | — | CN | disclosed |
| CN-106573073-B | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2021-09-28 | — | — | CN | disclosed |
| EP-1948243-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | Aeris Therapeutics, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007055950-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | AERIS THERAPEUTICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |