SCHEMBL51937

SCHEMBL51937

CC(CCC1CO1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.47
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45
CHRM1 P11229 2/20 0.45
CHRM3 P20309 2/20 0.45
TAAR1 Q96RJ0 5/20 0.44
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52157 0.81 TAAR1 (0.53) RIPK1CHRM2CHRM4CHRM5CHRM1
SCHEMBL10042384 0.80 RIPK1 (0.46) RIPK1TAAR1TRPA1
SCHEMBL4608900 0.78 MEN1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6280516 0.75 RIPK1 (0.67) RIPK1CHRM2CHRM1TAAR1TRPA1
SCHEMBL9319883 0.74 HTR1A (0.48) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11007531 0.74 AOC3 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28729189 0.74 TDP1 (0.59)
SCHEMBL8033824 0.73 RIPK1 (0.59) RIPK1CHRM2CHRM1TAAR1TRPA1
SCHEMBL8196637 0.73 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7731055 0.73 CYP19A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535707-B Pneumatic tire 横滨橡胶株式会社 2021-05-25 CN disclosed
EP-2508342-B1 INNER LINER FOR PNEUMATIC TIRE, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-04-01 EP disclosed
EP-2508343-B1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-03-11 EP disclosed
EP-2554372-B1 MULTILAYERED STRUCTURE AND LAMINATE AND METHOD FOR PRODUCTION OF THE SAME KURARAY CO (JP) 2020-01-08 EP disclosed
EP-2857451-B1 PNEUMATIC TIRE YOKOHAMA RUBBER CO LTD (JP) 2019-05-08 EP disclosed
EP-2623315-B1 MULTILAYERED STRUCTURE, INNER LINER HAVING THE SAME, AND PNEUMATIC TIRE KURARAY CO (JP) 2019-04-17 EP disclosed
EP-2716445-B1 MULTI-LAYERED STRUCTURE, INNER LINER FOR PNEUMATIC TIRE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2019-04-10 EP disclosed
US-10189980-B2 Process for producing thermoplastic resin composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2019-01-29 US disclosed
US-10183432-B2 Inner liner for pneumatic tire, method for producing the same, and pneumatic tire KURARAY CO., LTD. (JP) 2019-01-22 US disclosed
EP-2716444-B1 MULTI-LAYER STRUCTURE, INNER LINER FOR PNEUMATIC TIRE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2019-01-02 EP disclosed
CN-101010362-A Multilayered pellet comprising ethylene/vinyl alcohol copolymer resin compositions KURARAY CO (JP) 2007-08-01 CN disclosed
EP-1785446-A1 MULTILAYERED PELLET COMPRISING ETHYLENE/VINYL ALCOHOL COPOLYMER RESIN COMPOSITIONS KURARAY CO., LTD. (JP) 2007-05-16 EP disclosed
CN-1294198-C Resin composition and multi-layer structures KURARAY CO (JP) 2007-01-10 CN disclosed
CN-1231501-C Modified ethylene-vinyl alcohol copolymer and method for producing same KURARAY CO (JP) 2005-12-14 CN disclosed
CN-1649956-A Resin composition and multi-layer structures KURARAY CO (JP) 2005-08-03 CN disclosed
US-20050147778-A1 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2005-07-07 US disclosed
EP-1479725-A1 RESIN COMPOSITION AND MULTI-LAYER STRUCTURES Kuraray Co., Ltd. (JP) 2004-11-24 EP disclosed
US-20040096683-A1 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2004-05-20 US disclosed
EP-1403289-A1 MODIFIED ETHYLENE−VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF Kuraray Co., Ltd. (JP) 2004-03-31 EP disclosed
CN-1464883-A Modified ethylene-vinyl alcohol copolymer and method for producing same KURARAY CO (JP) 2003-12-31 CN disclosed