Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25266534 | 1.00 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL30427471 | 1.00 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL28635019 | 0.86 | MAPT (0.62) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL30932805 | 0.86 | MAPT (0.54) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL15465921 | 0.86 | MAPT (0.62) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL9393008 | 0.85 | RAB9A (0.55) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL30485178 | 0.85 | LTA4H (0.60) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30337968 | 0.85 | MAPT (0.53) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL1614525 | 0.84 | BACE1 (0.54) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL5145729 | 0.84 | BACE1 (0.54) | MEN1KMT2AMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127144-A | PRODUCING HETEROLOGOUS PROTEINS BY INCUBATING STREPTOMYCES CELL TRANSFORMED WITH NUCLEIC ACID EXPRESSION CONSTRUCT IN PRESENCE OF PEPTIDE-SUSBSTITUTED CHLOROMETHYLKETONE AMINOPEPTIDASE INHIBITOR HAVING DEFINED STRUCTURE | CANGENE CORPORATION (CA) | 2000-10-03 | — | — | US | claimed |
| EP-0122151-B1 | PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1989-02-15 | — | — | EP | claimed |
| US-4783402-A | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1988-11-08 | — | — | US | claimed |
| EP-0165905-A1 | Diagnostic assay method for the detection of oral pathogenic bacteria mixtures | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1985-12-27 | — | — | EP | claimed |
| EP-0122151-A2 | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | claimed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | claimed |
| WO-2023088470-A1 | PROBIOTIC COMPOSITIONS FOR TREATMENT OF HAIR LOSS | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2023-05-25 | — | — | WO | disclosed |
| US-20170172957-A1 | D-SERINE TRANSPORTER INHIBITORS AS PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLERGAN, INC. | 2017-06-22 | — | — | US | disclosed |
| EP-2714029-B1 | D-SERINE TRANSPORTER INHIBITORS AS PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLERGAN INC (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9415031-B2 | D-serine transporter inhibitors as pharmaceutical compositions for the treatment of visual system disorders | ALLERGAN, INC. (US) | 2016-08-16 | — | — | US | disclosed |
| US-20140221453-A1 | D-SERINE TRANSPORTER INHIBITORS AS PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISUAL SYSTEM DISORDERS | ALLERGAN, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8741955-B2 | D-serine transporter inhibitors as pharmaceutical compositions for the treatment of central nervous system disorders | ALLERGAN, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-8735451-B2 | D-serine transporter inhibitors as pharmaceutical compositions for the treatment of visual system disorders | ALLERGAN, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-6387650-B1 | INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES | BIOCONTROL SYSTEMS, INC. | 2002-05-14 | — | — | US | disclosed |
| EP-0165905-B1 | DIAGNOSTIC ASSAY METHOD FOR THE DETECTION OF ORAL PATHOGENIC BACTERIA MIXTURES | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0122151-B1 | PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1989-02-15 | — | — | EP | disclosed |
| US-4783402-A | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0122151-A2 | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4208480-A | Method, reagents and apparatus for the rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |