Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272976 | 0.65 | — | — | |
| SCHEMBL17477269 | 0.65 | KDM4E (0.31) | — | |
| SCHEMBL8892851 | 0.65 | THRB (0.47) | SMN1; SMN2BRD4 | |
| SCHEMBL5515974 | 0.64 | SMN1; SMN2 (0.41) | SMN1; SMN2ADORA1BRD4 | |
| SCHEMBL8912926 | 0.64 | SMN1; SMN2 (0.47) | SMN1; SMN2BRD4 | |
| SCHEMBL10543319 | 0.62 | SMN1; SMN2 (0.40) | SMN1; SMN2ADORA1 | |
| SCHEMBL17566 | 0.60 | — | — | |
| SCHEMBL2948892 | 0.60 | TP53 (0.56) | SMN1; SMN2BRD4 | |
| SCHEMBL244740 | 0.60 | — | — | |
| SCHEMBL2200767 | 0.60 | TP53 (0.56) | SMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976533-A2 | TRITERPENEQUINONE AND TRITERPENEPHENOL DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF TUMORS AND PARASITIC DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2008-10-08 | — | — | EP | claimed |
| WO-2007077203-A2 | TRITERPENEQUINONE AND TRITERPENEPHENOL DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF TUMORS AND PARASITIC DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2007-07-12 | — | — | WO | claimed |
| EP-1976533-A2 | TRITERPENEQUINONE AND TRITERPENEPHENOL DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF TUMORS AND PARASITIC DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007077203-A2 | TRITERPENEQUINONE AND TRITERPENEPHENOL DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF TUMORS AND PARASITIC DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2007-07-12 | — | — | WO | disclosed |