SCHEMBL4609543

SCHEMBL4609543

CCCCCCCCC[Al](CCCCCCCCC)CCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 7/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL6575954 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL15063 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9350922 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL80948 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
Hexane SCHEMBL1047425 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL23040209 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL149096 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6292836 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL14784986 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9506036 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365848-B2 Method for preparing high viscosity index poly-alpha-olefin CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-07-22 US claimed
CN-116023562-B Production process of poly alpha-olefin 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-116023534-B Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2025-03-21 CN claimed
CN-116023532-B Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2025-02-11 CN claimed
CN-116023562-A Production process of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116023532-A Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116023534-A Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-112745403-B Preparation method of poly-alpha-olefin 中国石油化工股份有限公司 2023-02-17 CN claimed
US-20220403278-A1 METHOD FOR PREPARING HIGH VISCOSITY INDEX POLY-ALPHA-OLEFIN CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-12-22 US claimed
US-20220389133-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-12-08 US claimed
CN-112745415-B Method for preparing poly-alpha-olefin with high viscosity index 中国石油化工股份有限公司 2022-09-09 CN claimed
EP-4053175-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2022-09-07 EP claimed
CN-111269343-B High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2021-08-17 CN claimed
WO-2021083307-A1 METHOD FOR PREPARING HIGH VISCOSITY INDEX POLY-α-OLEFIN 中国石油化工股份有限公司 2021-05-06 WO claimed
WO-2021083309-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国石油化工股份有限公司 2021-05-06 WO claimed
CN-112745403-A Preparation method of poly-alpha-olefin 中国石油化工股份有限公司 2021-05-04 CN claimed
CN-112745415-A Method for preparing poly-alpha-olefin with high viscosity index 中国石油化工股份有限公司 2021-05-04 CN claimed
CN-111269343-A High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2020-06-12 CN claimed
CN-1995081-A Double-component catalyst system for dicyclopentadiene loop-opening, replacement and polymerization and its polymerization process SHANGHAI XINTIANHE RESIN CO LT (CN) 2007-07-11 CN claimed
US-12365848-B2 Method for preparing high viscosity index poly-alpha-olefin CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-07-22 US disclosed
CN-116020416-B Method for removing metallocene catalyst 中国石油化工股份有限公司 2025-06-17 CN disclosed
CN-116023562-B Production process of poly alpha-olefin 中国石油化工股份有限公司 2025-04-18 CN disclosed
CN-116023534-B Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2025-03-21 CN disclosed
CN-116023532-B Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2025-02-11 CN disclosed
CN-119192435-A Supported metallocene catalyst and preparation method and application thereof 北京国达恒泰科贸有限责任公司 2024-12-27 CN disclosed
CN-118184686-A Intermittent preparation method and continuous preparation method of long carbon chain alkyl aluminum 潍坊达奥催化剂有限公司 2024-06-14 CN disclosed
CN-117756967-A Silicon bridged metallocene catalyst and application thereof 上海化工研究院有限公司 2024-03-26 CN disclosed
CN-116023532-A Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN disclosed
CN-116023562-A Production process of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN disclosed
CN-116023534-A Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN disclosed
CN-116020416-A Method for removing metallocene catalyst 中国石油化工股份有限公司 2023-04-28 CN disclosed
CN-112745403-B Preparation method of poly-alpha-olefin 中国石油化工股份有限公司 2023-02-17 CN disclosed
US-20220403278-A1 METHOD FOR PREPARING HIGH VISCOSITY INDEX POLY-ALPHA-OLEFIN CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-12-22 US disclosed
US-20220389133-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-12-08 US disclosed
CN-112745415-B Method for preparing poly-alpha-olefin with high viscosity index 中国石油化工股份有限公司 2022-09-09 CN disclosed
EP-4053175-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2022-09-07 EP disclosed
CN-111269343-B High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2021-08-17 CN disclosed
WO-2021083307-A1 METHOD FOR PREPARING HIGH VISCOSITY INDEX POLY-α-OLEFIN 中国石油化工股份有限公司 2021-05-06 WO disclosed
WO-2021083309-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国石油化工股份有限公司 2021-05-06 WO disclosed
CN-112745415-A Method for preparing poly-alpha-olefin with high viscosity index 中国石油化工股份有限公司 2021-05-04 CN disclosed
CN-112745403-A Preparation method of poly-alpha-olefin 中国石油化工股份有限公司 2021-05-04 CN disclosed
CN-111269343-A High molecular weight and ultrahigh molecular weight maleic anhydride-styrene monomer alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2020-06-12 CN disclosed
EP-2962735-B1 METHOD FOR PREVENTING AND EXTINGUISHING FIRE YAMATO PROTEC CORP (JP) 2018-10-31 EP disclosed
US-9839800-B2 Method for preventing and extinguishing fire YAMATO PROTEC CORPORATION (JP) 2017-12-12 US disclosed
US-20160023025-A1 METHOD FOR PREVENTING AND EXTINGUISHING FIRE YAMATO PROTEC CORPORATION (JP) 2016-01-28 US disclosed
EP-2962735-A1 METHOD FOR PREVENTING AND EXTINGUISHING FIRE Yamato Protec Corporation (JP) 2016-01-06 EP disclosed
WO-2014105272-A1 OXYGENATE REMOVAL FROM ORGANOMETALLIC COMPOUNDS ALBEMARLE CORPORATION (US) 2014-07-03 WO disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
EP-1419182-B1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORP (JP) 2008-10-15 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed
CN-1995081-A Double-component catalyst system for dicyclopentadiene loop-opening, replacement and polymerization and its polymerization process SHANGHAI XINTIANHE RESIN CO LT (CN) 2007-07-11 CN disclosed
EP-1419182-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE Bridgestone Corporation (JP) 2004-05-19 EP disclosed
WO-2003018644-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2003-03-06 WO disclosed
EP-0834519-B1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN JAPAN POLYOLEFINS CO LTD (JP) 2002-03-06 EP disclosed
US-6121182-A A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES JAPAN POLYOLAFINS CO., LTD. (JP) 2000-09-19 US disclosed
US-6096680-A REUSABLE ALUMINUM FRIEDEL-CRAFTS CATALYSTS; FORMED FROM AN ALUMINUM TRIHALIDE, ALKALI METAL HALIDE OR PSEUDOHALIDE, ALKALINE EARTH METAL HALIDE, QUATERNARY AMMONIUM, PHOSPHONIUM AND/OR SULFONIUM SALT AND AN AROMATIC HYDROCARBON ALBEMARLE CORPORATION (US) 2000-08-01 US disclosed
EP-0923584-A1 PRODUCTION AND UTILIZATION OF TRI-(BETA-BRANCHED ALKYL)ALUMINUM COMPOUNDS ALBEMARLE CORPORATION (US) 1999-06-23 EP disclosed
US-5859302-A Processes employing reusable aluminum catalysts ALBEMARLE CORPORATION (US) 1999-01-12 US disclosed
EP-0838447-A1 Processes employing reusable aluminum catalysts ALBEMARLE CORPORATION (US) 1998-04-29 EP disclosed
EP-0834519-A1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN Japan Polyolefins Co., Ltd. (JP) 1998-04-08 EP disclosed
WO-1998008852-A1 PRODUCTION AND UTILIZATION OF TRI-(BETA-BRANCHED ALKYL)ALUMINUM COMPOUNDS ALBEMARLE CORPORATION (US) 1998-03-05 WO disclosed
EP-0578473-B1 Catalyst for polymerization of olefin and process for producing olefin polymer SHOWA DENKO KK (JP) 1997-11-19 EP disclosed
US-5686640-A DIMERIZATION, REACTIVE DISTILLATION, PURIFICATION ALBEMARLE CORPORATION (US) 1997-11-11 US disclosed
US-5476825-A Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound SHOWA DENKO K.K. (JP) 1995-12-19 US disclosed
EP-0634426-A1 Process for the preparation of amorphous or little cristalline copolymers or terpolymers of olefins HÜLS AKTIENGESELLSCHAFT (DE) 1995-01-18 EP disclosed
EP-0578473-A1 Catalyst for polymerization of olefin and process for producing olefin polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1994-01-12 EP disclosed
US-5064800-A Organolithium Compound, Barium, Strontium or Calcium Alcoholate or Thiolate, Trialkylaluminum SHELL OIL COMPANY (US) 1991-11-12 US disclosed
EP-0434131-A2 Anionic polymerization catalyst compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-26 EP disclosed
US-4996273-A Organolithium compound, barium, strontium, or calcium alcoholate or thiolate, and trialkylaluminum compound; conjugated diene polymer or copolymer SHELL OIL COMPANY (US) 1991-02-26 US disclosed
US-4066683-A PROCESS FOR THE PREPARATION OF DIAMINOMALEONITRILE NIPPON CHEMICALS CO., LTD. (JA) 1978-01-03 US disclosed
US-4066683-A PROCESS FOR THE PREPARATION OF DIAMINOMALEONITRILE NIPPON CHEMICALS CO., LTD. (JA) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389133-A1 METALLOCENE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PPIL4, PIN1, PPIL1 TSHR 3801/4885THRB 4301/4885DNM1 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.