Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609561 | 0.84 | CHRNB4 (0.39) | NPSR1MEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL411023 | 0.79 | BACE1 (0.44) | MEN1KMT2ACYP11B1CYP11B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3773493 | 0.74 | CHRNB4 (0.40) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL26094881 | 0.73 | MEN1 (0.35) | MEN1KMT2ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL3143008 | 0.73 | CHRNB4 (0.39) | MEN1KMT2ACHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10501932 | 0.73 | SMN1; SMN2 (0.49) | NPSR1MEN1KMT2AMAPTALOX12 | |
| Hydrochloric Acid SCHEMBL3773488 | 0.72 | CHRNB4 (0.39) | MEN1KMT2ACHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2436276 | 0.72 | CLK4 (0.52) | NPSR1MEN1KMT2AMAPTALOX15 | |
| SCHEMBL30189821 | 0.71 | SQOR (0.40) | MEN1KMT2AMAPTGCGRMAPK14 | |
| SCHEMBL18557563 | 0.69 | MEN1 (0.49) | NPSR1MEN1KMT2AMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085750-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-08-02 | — | — | WO | disclosed |