Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931950 | 0.81 | KDM4E (0.31) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL31210013 | 0.75 | KDM4E (0.33) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL11266183 | 0.75 | KDM1A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL17241784 | 0.73 | KDM4E (0.30) | MEN1KMT2AKDM4E | |
| SCHEMBL24343229 | 0.69 | PPIA (0.33) | — | |
| SCHEMBL27642717 | 0.65 | MAPT (0.43) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL24593288 | 0.62 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL4965862 | 0.62 | KDM1A (0.36) | GAAKDM4ETSHR | |
| SCHEMBL2049681 | 0.62 | MEN1 (0.41) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL23838398 | 0.61 | GPR3 (0.36) | MEN1KMT2AMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |