SCHEMBL4609661

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4609664	1.00	IDO1 (0.51)	IDO1TDP1SLC6A2SLC6A4SLC6A3
	SCHEMBL1170735	0.85	TDP1 (0.49)	IDO1TDP1SLC6A2SLC6A4SLC6A3
	SCHEMBL14502702	0.80	ALDH1A1 (0.47)	IDO1TDP1SLC6A2SLC6A4SLC6A3
	SCHEMBL4609594	0.80	ALDH1A1 (0.47)	IDO1TDP1SLC6A2SLC6A4SLC6A3
	SCHEMBL4609592	0.80	ALDH1A1 (0.47)	IDO1TDP1SLC6A2SLC6A4SLC6A3
	SCHEMBL3431728	0.79	TDP1 (0.53)	TDP1ALDH1A1GLATP53CYP3A4
	SCHEMBL11017322	0.79	TDP1 (0.53)	TDP1SLC6A2SLC6A4SLC6A3ALDH1A1
	SCHEMBL6743415	0.78	TDP1 (0.39)	IDO1TDP1ALDH1A1GLATP53
	SCHEMBL6742323	0.78	TDP1 (0.39)	IDO1TDP1ALDH1A1GLATP53
	SCHEMBL17226943	0.78	TDP1 (0.39)	IDO1TDP1ALDH1A1GLATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.