SCHEMBL460988

SCHEMBL460988

CC(=O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALOX15 P16050 1/20 0.43
LGALS8 O00214 2/20 0.42
CD69 Q07108 1/20 0.42
SLC28A3 Q9HAS3 4/20 0.42
ALDH1A1 P00352 1/20 0.42
THRB P10828 1/20 0.42
HSD17B10 Q99714 1/20 0.41
TSHR P16473 1/20 0.41
PYGB P11216 1/20 0.41
BLM P54132 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27921424 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL8648898 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL19475556 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL7094225 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL2413753 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL25166887 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL1898656 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL181028 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
Hydrochloric Acid SCHEMBL28256651 0.98 LMNA (0.42) LMNAKDM4EALOX15LGALS8CD69
Ammonia Solution, Strong SCHEMBL27636528 0.98 LMNA (0.42) LMNAKDM4EALOX15LGALS8CD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024848-A1 METHODS AND COMPOSITIONS FOR INCREASING ENZYME ACTIVITY IN THE CNS ArmaGen Technologies, Inc. (US) 2016-06-01 EP claimed
WO-2015012944-A1 METHODS AND COMPOSITIONS FOR INCREASING ENZYME ACTIVITY IN THE CNS ARMAGEN TECHNOLOGIES, INC (US) 2015-01-29 WO claimed
EP-4337774-A1 PROGRAMMABLE NANOENCAPSULATION FOR DELIVERY OF PROBIOTICS IN VIVO The Trustees of Columbia University in the City of New York (US) 2024-03-20 EP disclosed
EP-4225338-A1 ENGINEERED PROBIOTICS FOR EXPRESSION OF FIBER-SYNTHESIZING ENZYMES IN GUT Zbiotics Company (US) 2023-08-16 EP disclosed
WO-2023110854-A1 METHODS OF PRODUCTION OF HEPAROSAN, HEPARAN SULFATE AND HEPARIN IN YEAST GENHTIS FINE CHEMICALS GMBH (DE) 2023-06-22 WO disclosed
WO-2022241107-A1 PROGRAMMABLE NANOENCAPSULATION FOR DELIVERY OF PROBIOTICS IN VIVO THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-11-17 WO disclosed
EP-3119894-A1 COTTON FIBERS WITH INCREASED GLUCOSAMINE CONTENT Bayer CropScience NV (BE) 2017-01-25 EP disclosed
EP-3024848-A1 METHODS AND COMPOSITIONS FOR INCREASING ENZYME ACTIVITY IN THE CNS ArmaGen Technologies, Inc. (US) 2016-06-01 EP disclosed
WO-2015140191-A1 COTTON FIBERS WITH INCREASED GLUCOSAMINE CONTENT BAYER CROPSCIENCE NV (BE) 2015-09-24 WO disclosed
WO-2015012944-A1 METHODS AND COMPOSITIONS FOR INCREASING ENZYME ACTIVITY IN THE CNS ARMAGEN TECHNOLOGIES, INC (US) 2015-01-29 WO disclosed
EP-2596123-A2 CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE Shire Human Genetic Therapies, Inc. (US) 2013-05-29 EP disclosed
EP-2585105-A2 TREATMENT OF SANFILIPPO SYNDROME TYPE B Shire Human Genetic Therapies, Inc. (US) 2013-05-01 EP disclosed
WO-2012012742-A2 CRYSTAL STRUCTURE OF HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2012-01-26 WO disclosed
WO-2011163652-A2 TREATMENT OF SANFILIPPO SYNDROME TYPE B SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2011-12-29 WO disclosed
EP-1185283-A4 NOVEL THERAPEUTIC USE OF VIRAL INFLAMMATION MODULATORY PROTEIN IN BLOCKING XENOGRAFT REJECTION KING FAISAL SPECIALIST HOSPITA (SA) 2003-07-02 EP disclosed
EP-1185283-A1 NOVEL THERAPEUTIC USE OF VIRAL INFLAMMATION MODULATORY PROTEIN IN BLOCKING XENOGRAFT REJECTION KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTRE (SA) 2002-03-13 EP disclosed
WO-2000071147-A1 NOVEL THERAPEUTIC USE OF VIRAL INFLAMMATION MODULATORY PROTEIN IN BLOCKING XENOGRAFT REJECTION KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTRE (SA) 2000-11-30 WO disclosed