SCHEMBL181028

SCHEMBL181028

CC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1N

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALOX15 P16050 1/20 0.43
LGALS8 O00214 2/20 0.42
CD69 Q07108 1/20 0.42
SLC28A3 Q9HAS3 4/20 0.42
ALDH1A1 P00352 1/20 0.42
THRB P10828 1/20 0.42
HSD17B10 Q99714 1/20 0.41
TSHR P16473 1/20 0.41
PYGB P11216 1/20 0.41
BLM P54132 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27921424 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL8648898 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL19475556 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL460988 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL7094225 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL2413753 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL25166887 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
SCHEMBL1898656 1.00 LMNA (0.43) LMNAKDM4EALOX15LGALS8CD69
Hydrochloric Acid SCHEMBL28256651 0.98 LMNA (0.42) LMNAKDM4EALOX15LGALS8CD69
Ammonia Solution, Strong SCHEMBL27636528 0.98 LMNA (0.42) LMNAKDM4EALOX15LGALS8CD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381246-A1 LIQUID FORMULATIONS COMPRISING MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES 89BIO, INC. (US) 2025-12-18 US disclosed
US-20250333460-A1 MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES AND USES THEREOF 89BIO LTD. (IL) 2025-10-30 US disclosed
US-20250282840-A1 METHODS OF TREATMENT USING MUTANT FGF-21 PEPTIDE CONJUGATES 89BIO LTD. (IL) 2025-09-11 US disclosed
US-12350314-B2 Liquid formulations comprising mutant FGF-21 peptide pegylated conjugates 89BIO, INC. (US) 2025-07-08 US disclosed
EP-4577563-A2 METHODS OF TREATMENT OF NASH USING MUTANT FGF-21 PEPTIDE CONJUGATES 89Bio, Inc. (US) 2025-07-02 EP disclosed
WO-2025043155-A1 THERAPEUTIC REGIMENS AND METHODS OF TREATMENT OF NASH USING MUTANT FGF-21 PEPTIDE CONJUGATES 89BIO, INC. (US) 2025-02-27 WO disclosed
US-20240307492-A1 LIQUID FORMULATIONS COMPRISING MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES 89BIO, INC. (US) 2024-09-19 US disclosed
US-12037376-B2 Methods of treatment using mutant FGF-21 peptide conjugates 89BIO LTD. (IL) 2024-07-16 US disclosed
US-20240116995-A1 MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES AND USES THEREOF 89BIO LTD. (IL) 2024-04-11 US disclosed
WO-2024044680-A2 METHODS OF TREATMENT OF NASH USING MUTANT FGF-21 PEPTIDE CONJUGATES 89BIO, INC. (US) 2024-02-29 WO disclosed
WO-2005070138-A2 O-LINKED GLYCOSYLATION OF PEPTIDES NEOSE TECHNOLOGIES, INC. (US) 2005-08-04 WO disclosed
US-20050143292-A1 Glycopegylated erythropoietin NOVO NORDISK A/S (DK) 2005-06-30 US disclosed
WO-2005055946-A2 GLYCOPEGYLATED GRANULOCYTE COLONY STIMULATING FACTOR NEOSE TECHNOLOGIES, INC. (US) 2005-06-23 WO disclosed
WO-2005055950-A2 GLYCOPEGYLATED FACTOR IX NEOSE TECHNOLOGIES, INC. (US) 2005-06-23 WO disclosed
WO-2005051327-A2 GLYCOPEGYLATED ERYTHROPOIETIN NEOSE TECHNOLOGIES, INC. (US) 2005-06-09 WO disclosed
WO-2005012484-A2 ANTIBODY-TOXIN CONJUGATES NEOSE TECHNOLOGIES, INC. (US) 2005-02-10 WO disclosed
WO-2004103275-A2 COMPOSITIONS AND METHODS FOR THE PREPARATION OF HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS NEOSE TECHNOLOGIES, INC. (US) 2004-12-02 WO disclosed
WO-2004091499-A2 INTRACELLULAR FORMATION OF PEPTIDE CONJUGATES NEOSE TECHNOLOGIES, INC. (US) 2004-10-28 WO disclosed
WO-2004083258-A2 BRANCHED WATER-SOLUBLE POLYMERS AND THEIR CONJUGATES NEOSE TECHNOLOGIES INC. (US) 2004-09-30 WO disclosed
CN-85107911-A The production method of ellipticine derivative 1987-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350314-B2 Liquid formulations comprising mutant FGF-21 peptide pegylated conjugates FGF1, FGFR1, FGF2 LMNA 4219/4885KDM4E 4725/4885ALOX15 1117/4885
US-20250282840-A1 METHODS OF TREATMENT USING MUTANT FGF-21 PEPTIDE CONJUGATES HDGF, FGF1, FGFR1 LMNA 3715/4885KDM4E 4314/4885ALOX15 2894/4885
US-20250381246-A1 LIQUID FORMULATIONS COMPRISING MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES FGF1, FGFR1, FGF2 LMNA 4219/4885KDM4E 4725/4885ALOX15 1117/4885
US-20250333460-A1 MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES AND USES THEREOF FGF1, FGF2, FGF23 LMNA 4316/4885KDM4E 3911/4885ALOX15 3315/4885
US-20240116995-A1 MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES AND USES THEREOF FGF1, FGF2, FGF23 LMNA 4316/4885KDM4E 3911/4885ALOX15 3315/4885
US-20050143292-A1 Glycopegylated erythropoietin EPOR, UGGT1, GNE LMNA 2220/4885KDM4E 2672/4885ALOX15 1826/4885
US-20240307492-A1 LIQUID FORMULATIONS COMPRISING MUTANT FGF-21 PEPTIDE PEGYLATED CONJUGATES FGF1, FGFR1, FGF2 LMNA 4219/4885KDM4E 4725/4885ALOX15 1117/4885
US-12037376-B2 Methods of treatment using mutant FGF-21 peptide conjugates HDGF, FGF1, FGFR1 LMNA 3715/4885KDM4E 4314/4885ALOX15 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.