Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588348 | 0.88 | CYP3A4 (0.63) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL7122749 | 0.87 | TDP1 (0.55) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| Nitrogen SCHEMBL28276545 | 0.85 | CYP3A4 (0.59) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL10034862 | 0.84 | TDP1 (0.57) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL7921397 | 0.84 | TDP1 (0.51) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL7566464 | 0.83 | POLB (0.59) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL6549530 | 0.83 | TDP1 (0.50) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1922592 | 0.82 | GAA (0.56) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1752261 | 0.82 | TDP1 (0.55) | HTTPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL10889681 | 0.82 | TDP1 (0.55) | HTTPOLBTDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021149703-A1 | COLORED DISPERSION, RECORDING MEDIUM, AND TEXTILE PRINTING METHOD FOR HYDROPHOBIC FIBERS | 日本化薬株式会社 | 2021-07-29 | — | — | WO | disclosed |
| EP-3676255-A1 | THERAPEUTIC INDAZOLES | Rutgers, The State University University Of New Jersey (US) | 2020-07-08 | — | — | EP | disclosed |
| CN-106715430-B | inhibition of transient receptor potential A1 ion channels | 伊莱利利公司 | 2019-09-17 | — | — | CN | disclosed |
| WO-2019046467-A1 | THERAPEUTIC INDAZOLES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-03-07 | — | — | WO | disclosed |
| US-9701691-B2 | Thienopyrimidine compounds | HOFFMAN-LA ROCHE INC. (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2802590-B1 | THIENOPYRIMIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-03-01 | — | — | EP | disclosed |
| CN-104159904-B | Thienopyrimidine compounds | 霍夫曼-拉罗奇有限公司 | 2016-12-14 | — | — | CN | disclosed |
| US-9309185-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2016-04-12 | — | — | US | disclosed |
| US-9012691-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2015-04-21 | — | — | US | disclosed |
| EP-2802590-A1 | THIENOPYRIMIDINE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2014-11-19 | — | — | EP | disclosed |
| US-5668260-A | Tetrakisazo Compounds, the method of preparation thereof and the process of pyeing | HOECHT AKTIENGE SELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| US-5609796-A | MIXTURE OF DISAZO AND TRISAZO DYES, METALLIZED DYES, IN POLYVINYL ALCOHOL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0738764-A1 | Tetrakisazo compounds, their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0648814-A1 | Dye containing polarizing film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-4431585-A | THIAZOLE AND THIOPHENE DYES; DIAZOTIZATION; COUPLING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | disclosed |
| EP-0035671-A1 | Water-insoluble azo dyestuffs, methods for their preparation and their use in dyeing and printing synthetic hydrophobic fibre materials | CASSELLA Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4124593-A | ANTICONVULSANTS, EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4058518-A | Water-insoluble monoazo 3-cyano-4-methyl-6-hydroxy-2-pyridine dyestuffs | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3993441-A | MONOAZO DYE | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |