Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549530 | 0.95 | TDP1 (0.50) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL3477025 | 0.94 | KCNH2 (0.49) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL11783489 | 0.94 | KCNH2 (0.49) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL7122749 | 0.90 | TDP1 (0.55) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL2566274 | 0.89 | CYP3A4 (0.53) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL10912325 | 0.86 | ALDH1A1 (0.55) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL460989 | 0.84 | HTT (0.66) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL28744999 | 0.83 | ALDH1A1 (0.55) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL7929953 | 0.83 | POLB (0.70) | TDP1ALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL16497028 | 0.83 | CYP3A4 (0.50) | TDP1ALDH1A1CYP3A4HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870143-A1 | TRIAZOLE COMPOUNDS AS ANTIVIRALS | F. Hoffmann-La Roche AG (CH) | 2015-05-13 | — | — | EP | disclosed |
| WO-2014006066-A1 | TRIAZOLE COMPOUNDS AS ANTIVIRALS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-01-09 | — | — | WO | disclosed |
| EP-0661350-B1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON CATALYTIC CHEM IND (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5817843-A | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5608091-A | SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0661350-A1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0362725-A1 | Process for producing water insoluble azo dyes on the fibre according to the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |