Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893629 | 0.87 | GAA (0.59) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1520431 | 0.87 | GAA (0.59) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL8373001 | 0.85 | TSHR (0.55) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL260788 | 0.84 | CYP1A2 (0.51) | GAATHRBTDP1ALDH1A1TSHR | |
| SCHEMBL29367937 | 0.84 | CYP1A2 (0.51) | GAATHRBTDP1ALDH1A1TSHR | |
| SCHEMBL460989 | 0.82 | HTT (0.66) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL10034862 | 0.82 | TDP1 (0.57) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29449526 | 0.82 | PTPRC (0.52) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL679942 | 0.82 | PTPRC (0.52) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL31536502 | 0.81 | LOXL2 (0.48) | GAATHRBTDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309185-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2016-04-12 | — | — | US | claimed |
| US-9012691-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2015-04-21 | — | — | US | claimed |
| US-20140121415-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| US-20140121414-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| CN-113582867-B | Continuous synthesis method of 2-acetamido-5-nitrobenzyl ether | 山东师范大学实验厂有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113582867-A | Continuous synthesis method of 2-acetamido-5-nitrobenzyl ether | 山东师范大学实验厂 | 2021-11-02 | — | — | CN | disclosed |
| US-10968392-B2 | Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer | JNC CORPORATION (JP) | 2021-04-06 | — | — | US | disclosed |
| EP-3134408-B1 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2912008-B1 | PROCESS FOR PREPARING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE AND SALTS THEREOF | NOXELL CORP (US) | 2020-08-05 | — | — | EP | disclosed |
| CN-110551508-A | Liquid crystal aligning agent for photo-alignment, liquid crystal alignment film, liquid crystal display element, method for forming liquid crystal alignment film, method for forming liquid crystal display element, and polyamic acid or derivative thereof | JNC CORP | 2019-12-10 | — | — | CN | disclosed |
| US-20190127643-A1 | LIQUID CRYSTAL ALIGNING AGENT FOR PHOTOALIGNMENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE USING IT, AND DIAMINE AND POLYMER | JNC CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| CN-104768916-B | Process for preparing 2-methoxymethyl-1, 4-benzenediamine and salts thereof | 诺赛尔股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995002848-A1 | MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |
| EP-0010348-A1 | Heterocyclic trichloromethyl derivatives, process for their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968392-B2 | Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer | DDT, DCLRE1A, DVL1 | GAA 4503/4885THRB 4760/4885TDP1 188/4885 |
| US-20140121414-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | KRT18, VIM, F12 | GAA 3585/4885THRB 4663/4885TDP1 3382/4885 |
| US-20140121415-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | KRT18, VIM, F12 | GAA 3585/4885THRB 4663/4885TDP1 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.