Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608613 | 0.89 | ALOX15 (0.38) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL4919218 | 0.86 | ALOX15 (0.36) | ALDH1A1ALOX15TDP1 | |
| SCHEMBL4608403 | 0.83 | ALOX15 (0.40) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL4883840 | 0.71 | ALOX15 (0.42) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL6251037 | 0.70 | ALOX15 (0.50) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL3759620 | 0.70 | ALOX15 (0.50) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL14548161 | 0.70 | ALOX15 (0.50) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL15457612 | 0.70 | ALOX15 (0.50) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL5691783 | 0.68 | ALOX15 (0.39) | ALDH1A1ALOX15TDP1LMNANFE2L2 | |
| SCHEMBL6252287 | 0.66 | ALOX15 (0.46) | ALDH1A1ALOX15TDP1LMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205566-A1 | OXIDIZED AMINOLIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-8466294-B2 | 1-aza-3,7-dioxabicyclo[3.3.0]octane compounds and their use as pro-fragrances | HENKEL AG & CO. KGAA (DE) | 2013-06-18 | — | — | US | disclosed |
| EP-1976855-B1 | 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES | HENKEL AG & CO KGAA (DE) | 2012-08-15 | — | — | EP | disclosed |
| US-20080305063-A1 | 1-aza-3,7-dioxabicyclo[3.3.0]octane compounds and their use as pro-fragrances | HENKEL AG & CO. KGAA (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-1976855-A1 | 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES | Henkel AG & Co. KGaA (DE) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007087977-A1 | 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES | HENKEL AG & CO. KGAA (DE) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305063-A1 | 1-aza-3,7-dioxabicyclo[3.3.0]octane compounds and their use as pro-fragrances | AZI2, CUTA, DNMT1 | ALDH1A1 460/4885ALOX15 477/4885TDP1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.