SCHEMBL4610102

SCHEMBL4610102

CCOC([SiH3])=C(OC)OCC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5421810 0.92 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL5421812 0.90 MGAM (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL20981381 0.88 MGAM (0.32) MGAMGAASIMGAM2
SCHEMBL360142 0.86 ALDH1A1 (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28040093 0.83 ALDH1A1 (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7776134 0.81 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
Alcohol SCHEMBL21493580 0.79 ALDH1A1 (0.33) MGAMGAASIMGAM2ALDH1A1
SCHEMBL17756695 0.72
SCHEMBL2360044 0.72 SOAT1 (0.31) SOAT1
SCHEMBL19858509 0.72 ALDH1A1 (0.48) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828392-B2 Low chloride compositions of olefinically functionalised siloxane oligomers based on alkoxysilanes EVONIK DEGUSSA GMBH (DE) 2017-11-28 US disclosed
US-20140296555-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2014-10-02 US disclosed
EP-1219650-B1 Star polymer colloidal stabilizers NAT STARCH CHEM INVEST (US) 2008-10-08 EP disclosed
US-6420479-B1 AMPHIPHILIC STAR POLYMER CROSSLINKING NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2002-07-16 US disclosed
EP-1219650-A2 Star polymer colloidal stabilizers National Starch and Chemical Investment Holding Corporation (US) 2002-07-03 EP disclosed