SCHEMBL7776134

SCHEMBL7776134

CCOC(OCC)=C([SiH3])OC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
ALOX15 P16050 1/20 0.32
SOAT1 P35610 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5421812 0.92 MGAM (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL20981381 0.91 MGAM (0.32) MGAMGAASIMGAM2
SCHEMBL360142 0.82 ALDH1A1 (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4610102 0.81 MGAM (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28040093 0.80 ALDH1A1 (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL5421810 0.78 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
Alcohol SCHEMBL21493580 0.76 ALDH1A1 (0.33) MGAMGAASIMGAM2ALDH1A1
SCHEMBL333268 0.71 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL23292820 0.71 ALDH1A1 (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL656787 0.71 ALDH1A1 (0.43) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2782951-B1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2019-01-02 EP disclosed
US-9828392-B2 Low chloride compositions of olefinically functionalised siloxane oligomers based on alkoxysilanes EVONIK DEGUSSA GMBH (DE) 2017-11-28 US disclosed
US-20140296555-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2014-10-02 US disclosed
EP-2782951-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES Evonik Degussa GmbH (DE) 2014-10-01 EP disclosed
WO-2013076032-A1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2013-05-30 WO disclosed
EP-0743347-B1 Water-based fluorine-containing paint CENTRAL GLASS CO LTD (JP) 2001-12-05 EP disclosed
EP-1123943-A1 Water-based fluorine-containing plant CENTRAL GLASS COMPANY, LIMITED (JP) 2001-08-16 EP disclosed
US-6174955-B1 FLUOROOLEFIN, VINYL COMPOUND, HYDROXY COMPOUND AND CARBOXY COMPOUND WITH HARDENER CENTRAL GLASS COMPANY, LIMITED (JP) 2001-01-16 US disclosed
US-5856394-A TETRAPOLYMERS OF FLUOROOLEFIN, VINYL ETHER OR ESTER, OMEGA-UNSATURATED ALKENOIC ACID, ALLYL ACETOACETATE OR ALKYLENE OXIDE DERIVATIVE, HYDRAZINE HARDENER CENTRAL GLASS COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0743347-A2 Water-based fluorine-containing paint CENTRAL GLASS COMPANY, LIMITED (JP) 1996-11-20 EP disclosed