Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590706 | 0.95 | IL4I1 (0.45) | IL4I1PDK2CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL4590985 | 0.94 | IL4I1 (0.45) | IL4I1PDK2CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL4590806 | 0.92 | IL4I1 (0.45) | IL4I1PDK2CYP11B1CYP11B2KMT2A | |
| SCHEMBL4591025 | 0.92 | IL4I1 (0.47) | IL4I1CYP11B1CYP11B2KMT2AGRM2 | |
| SCHEMBL4589984 | 0.88 | CYP11B1 (0.45) | IL4I1PDK2CYP11B1CYP11B2KMT2A | |
| SCHEMBL4590661 | 0.88 | CYP11B1 (0.46) | IL4I1CYP11B1CYP11B2L3MBTL1GRM2 | |
| SCHEMBL13940224 | 0.81 | IL4I1 (0.53) | IL4I1CYP11B1CYP11B2L3MBTL1GRM2 | |
| SCHEMBL4590656 | 0.79 | IL4I1 (0.41) | IL4I1CYP11B1CYP11B2GRM2SMN1; SMN2 | |
| SCHEMBL13939911 | 0.79 | IL4I1 (0.55) | IL4I1CYP11B1CYP11B2KMT2AGRM2 | |
| SCHEMBL4589224 | 0.78 | ADRA2A (0.46) | CYP11B1CYP11B2L3MBTL1GRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899321-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007000246-A1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING A SATURATED LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | claimed |