Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231514 | 0.98 | CES2 (0.53) | CES2ALDH1A1TSHRCA12CA1 | |
| SCHEMBL12231362 | 0.95 | CES2 (0.53) | CES2ALDH1A1TSHRCA12CA1 | |
| SCHEMBL12231363 | 0.91 | CES2 (0.57) | CES2ALDH1A1TSHRCA12CA1 | |
| SCHEMBL4122910 | 0.86 | CA12 (0.50) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL1941494 | 0.83 | ESR1 (0.46) | ALDH1A1TSHRTDP1NPSR1MEN1 | |
| SCHEMBL1260625 | 0.81 | CES2 (0.43) | CES2PDK2PDK4CNR2MAPT | |
| SCHEMBL3978477 | 0.78 | KDM4E (0.57) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL2302963 | 0.77 | ALDH1A1 (0.45) | CES2ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL4115726 | 0.76 | CA12 (0.55) | CES2ALDH1A1TSHRCA12CA1 | |
| SCHEMBL25262379 | 0.75 | TDP1 (0.56) | CES2ALDH1A1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101184722-B | Novel resorcinol derivatives for skin | UNILEVER NV | 2011-06-22 | — | — | CN | disclosed |
| US-7468464-B2 | Resorcinol derivatives for skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-7468464-B2 | Resorcinol derivatives for skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-7468464-B2 | Resorcinol derivatives for skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| EP-1861353-B1 | NOVEL RESORCINOL DERIVATIVES FOR SKIN | UNILEVER PLC (GB) | 2008-10-08 | — | — | EP | disclosed |
| EP-1861353-B1 | NOVEL RESORCINOL DERIVATIVES FOR SKIN | UNILEVER PLC (GB) | 2008-10-08 | — | — | EP | disclosed |
| US-20080131382-A1 | Novel Resorcinol Derivatives for Skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080131382-A1 | Novel Resorcinol Derivatives for Skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080131382-A1 | Novel Resorcinol Derivatives for Skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| CN-101184722-A | Novel resorcinol derivatives for skin | UNILEVER HOME & PERSONAL CARE (NL) | 2008-05-21 | — | — | CN | disclosed |
| EP-1861353-A1 | NOVEL RESORCINOL DERIVATIVES FOR SKIN | UNILEVER PLC (GB) | 2007-12-05 | — | — | EP | disclosed |
| US-20060210498-A1 | Novel resorcinol derivatives for skin | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2006-09-21 | — | — | US | disclosed |
| WO-2006097224-A1 | NOVEL RESORCINOL DERIVATIVES FOR SKIN | UNILEVER PLC (GB) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080131382-A1 | Novel Resorcinol Derivatives for Skin | NR1H2, CYP1B1, NR0B1 | CES2 451/4885ALDH1A1 692/4885TSHR 2710/4885 |
| US-20060210498-A1 | Novel resorcinol derivatives for skin | NR1H2, CYP1B1, NR0B1 | CES2 451/4885ALDH1A1 692/4885TSHR 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.