Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083300 | 0.97 | FFAR1 (0.50) | FFAR1FFAR4MTNR1AMTNR1B | |
| SCHEMBL2085300 | 0.95 | FFAR1 (0.45) | FFAR1FFAR4MTNR1AMTNR1B | |
| SCHEMBL2085155 | 0.91 | FFAR1 (0.49) | FFAR1FFAR4AKR1B1MTNR1AMTNR1B | |
| SCHEMBL4612420 | 0.89 | PTGER1 (0.43) | FFAR1MTNR1AMTNR1B | |
| SCHEMBL2085517 | 0.87 | FFAR1 (0.52) | FFAR1FFAR4MTNR1AMTNR1B | |
| SCHEMBL4611227 | 0.85 | KCNH2 (0.45) | FFAR1 | |
| SCHEMBL2084534 | 0.85 | FFAR1 (0.49) | FFAR1FFAR4 | |
| SCHEMBL2085568 | 0.82 | PTGER1 (0.45) | FFAR1FFAR4MTNR1AMTNR1B | |
| SCHEMBL4971788 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL2081667 | 0.81 | FFAR1 (0.49) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |