Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086110 | 0.91 | KCNH2 (0.44) | KCNH2OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4612375 | 0.89 | PPARA (0.43) | KCNH2OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL2083300 | 0.88 | FFAR1 (0.50) | FFAR1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL2083494 | 0.87 | FFAR1 (0.40) | KCNH2FFAR1ALDH1A1 | |
| SCHEMBL4610356 | 0.85 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL2082976 | 0.85 | PTGS2 (0.41) | FFAR1ALDH1A1 | |
| SCHEMBL2085519 | 0.83 | KDM4E (0.51) | FFAR1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL4969418 | 0.82 | FFAR1 (0.45) | KCNH2FFAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2087473 | 0.82 | KCNH2 (0.37) | KCNH2FFAR1 | |
| SCHEMBL2085155 | 0.81 | FFAR1 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |