SCHEMBL4610474

SCHEMBL4610474

NC(=O)Nc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
ALDH1A1 P00352 2/20 0.44
TSHR P16473 3/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 6/20 0.40
CA2 P00918 6/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CA12 O43570 3/20 0.40
CA9 Q16790 3/20 0.40
HTT P42858 3/20 0.38
LMNA P02545 2/20 0.38
RAB9A P51151 1/20 0.38
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6506531 0.89 GAA (0.38) GAAALDH1A1TSHRMAPK1HSD17B10
SCHEMBL21810569 0.77 GAA (0.55) GAATSHRMAPK1NPC1SMN1; SMN2
SCHEMBL3068709 0.75 GAA (0.53) GAAALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL2089237 0.74 GAA (0.46) GAATSHRMAPK1NPC1SMN1; SMN2
SCHEMBL2089240 0.74 GAA (0.46) GAATSHRMAPK1NPC1SMN1; SMN2
SCHEMBL3068715 0.74 GAA (0.42) GAAALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL10719505 0.73 MAOA (0.37) GAAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20560307 0.72 GAA (0.45) GAATSHRMAPK1NPC1SMN1; SMN2
SCHEMBL3072029 0.72 GAA (0.61) GAATSHRMAPK1NPC1SMN1; SMN2
SCHEMBL1726079 0.72 GAA (0.45) GAATSHRMAPK1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899141-A Chiral pentafluorophenyl urea compound and preparation method and application thereof 沈阳化工大学 2025-04-29 CN claimed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
CN-108583525-A Portable intelligent solar energy service station of washing car by oneself 蒋敏 2018-09-28 CN claimed
EP-1979747-A1 METHODS FOR INTERFERING WITH GLUCOCORTICOID INDUCED GASTRIC ACID SECRETION Merck Patent GmbH (DE) 2008-10-15 EP claimed
WO-2007121963-A1 METHODS FOR INTERFERING WITH DISEASE RELATED TO IMPAIRED MAST CELL ACTIVATION MERCK PATENT GMBH (DE) 2007-11-01 WO claimed
WO-2007087985-A1 METHODS FOR INTERFERING WITH GLUCOCORTICOID INDUCED GASTRIC ACID SECRETION MERCK PATENT GMBH (DE) 2007-08-09 WO claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
CN-119899141-A Chiral pentafluorophenyl urea compound and preparation method and application thereof 沈阳化工大学 2025-04-29 CN disclosed
CN-119899141-A Chiral pentafluorophenyl urea compound and preparation method and application thereof 沈阳化工大学 2025-04-29 CN disclosed
CN-119899141-A Chiral pentafluorophenyl urea compound and preparation method and application thereof 沈阳化工大学 2025-04-29 CN disclosed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
CN-108583525-A Portable intelligent solar energy service station of washing car by oneself 蒋敏 2018-09-28 CN disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 GAA 1890/4885ALDH1A1 3840/4885TSHR 4611/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 GAA 1890/4885ALDH1A1 3840/4885TSHR 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.