Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610474 | 0.89 | GAA (0.45) | GAAALDH1A1TSHRMAPK1HSD17B10 | |
| Phenylurea SCHEMBL6505098 | 0.71 | MAPT (0.66) | GAAALDH1A1TSHRHSD17B10KIF11 | |
| SCHEMBL2089240 | 0.71 | GAA (0.46) | GAATSHRMAPK1NPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5793900 | 0.71 | TSHR (0.59) | ALDH1A1TSHRCA2CA9L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL15533970 | 0.69 | ACHE (0.54) | ALDH1A1TSHRCA2L3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL5747984 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRCA2L3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL934980 | 0.69 | ACHE (0.54) | ALDH1A1TSHRCA2L3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL3906649 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRCA2L3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL31659099 | 0.69 | — | — | |
| Trifluoroacetic Acid SCHEMBL30509267 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | claimed |