SCHEMBL4610568

SCHEMBL4610568

COP(=O)(OC)C(=O)c1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.54
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
MMP3 P08254 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
PTK2B Q14289 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CDC25B P30305 2/20 0.46
PTPN1 P18031 1/20 0.46
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
ALOX12 P18054 1/20 0.45
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609949 0.82 PLK1 (0.50) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4610651 0.82 HPGD (0.54) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL11515536 0.82 KDM4E (0.50) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL28030348 0.81 PTK2B (0.65) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4609824 0.80 KMT2A (0.49) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4611380 0.80 NR4A1 (0.53) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4610499 0.80 PLK1 (0.47) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4610305 0.80 PTK2B (0.67) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4610988 0.79 PLK1 (0.46) PLK1NR4A1NR4A2NR4A3MMP3
SCHEMBL4610278 0.79 PLK1 (0.46) PLK1NR4A1NR4A2NR4A3MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1419182-B1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORP (JP) 2008-10-15 EP disclosed
CN-1293102-C Iron-based catalyst composition for producing syndiotactic 1, 2-polybutadiene BRIDGESTONE CORP (JP) 2007-01-03 CN disclosed
CN-1527844-A Iron-based catalyst composition for the manufacture of syndiotactic 1.2-polybutadiene ������������ʽ���� 2004-09-08 CN disclosed
EP-1419182-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6610804-B2 An iron compound, an alpha-acylphosphonate diester, and an organoaluminum compound BRIDGESTONE CORPORATION (JP) 2003-08-26 US disclosed
US-6576725-B1 Iron compound, organomagnesium compound, and alpha-acylphosphonate diester; addition polymerization BRIDGESTONE CORPORATION (JP) 2003-06-10 US disclosed
US-20030073790-A1 Iron-based catalyst composition for the manufacture of syndiotactic 1, 2-polybutadiene BRIDGESTONE CORP. 2003-04-17 US disclosed
US-20030073570-A1 Method of preparing oligomers of conjugated dienes with an iron-based catalyst composition BRIDGESTONE CORP. 2003-04-17 US disclosed
WO-2003018644-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2003-03-06 WO disclosed
EP-0042567-A2 Photopolymerisable mixtures with aroylphosphonic acid esters as photoinitiators BAYER AG (DE) 1981-12-30 EP disclosed