SCHEMBL28030348

SCHEMBL28030348

C=C(c1cccc2ccccc12)P(=O)(OC)OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
PLK1 P53350 1/20 0.49
MMP3 P08254 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CDC25B P30305 2/20 0.41
PTPN1 P18031 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ALOX12 P18054 1/20 0.41
POLB P06746 2/20 0.40
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4610568 0.81 PLK1 (0.54) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL10040032 0.79 PTK2B (0.74) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL30266359 0.79 PTK2B (1.00) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL10039983 0.79 PTK2B (1.00) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL30266106 0.78 PTK2B (0.53) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL28030389 0.77 ALDH1A1 (0.46) PTK2BL3MBTL1CDC25BPTPN1KMT2A
SCHEMBL1869296 0.73 PTK2B (0.59) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL3698429 0.73 PTK2B (0.55) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL28980095 0.71 PTK2B (0.62) PTK2BL3MBTL1PLK1MMP3HDAC8
SCHEMBL3794319 0.71 PLK1 (0.54) PTK2BL3MBTL1PLK1MMP3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926867-B Preparation method for alkenyl phosphonate compound 北京大学 2017-04-19 CN disclosed
CN-104926867-A Preparation method for alkenyl phosphate compound UNIV BEIJING 2015-09-23 CN disclosed