Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TARDBP | Q13148 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 1.00 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lipoic Acid, Alpha SCHEMBL51065 | 1.00 | HSD17B10 (1.00) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Lipoic Acid, Alpha SCHEMBL1981737 | 1.00 | HSD17B10 (1.00) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Thioctic Acid SCHEMBL7924 | 1.00 | HSD17B10 (1.00) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Lipoic Acid, Alpha SCHEMBL2128472 | 1.00 | HSD17B10 (1.00) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL25257437 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Thioctic Acid SCHEMBL6037631 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Lipoic Acid, Alpha SCHEMBL6037633 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL7914749 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Thioctic Acid SCHEMBL8948222 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| Lipoic Acid, Alpha SCHEMBL4898905 | 0.98 | HSD17B10 (0.96) | HSD17B10KMT2ATARDBPCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984348-A2 | METHOD FOR IMPROVING THE ORAL ADMINISTRATION OF ALPHA-LIPOIC ACID | Multi Formulations Ltd. (CA) | 2008-10-29 | — | — | EP | disclosed |
| EP-1931760-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | The University of Alabama (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007095117-A2 | METHOD FOR IMPROVING THE ORAL ADMINISTRATION OF ALPHA-LIPOIC ACID | MULTI FORMULATIONS LTD. (CA) | 2007-08-23 | — | — | WO | disclosed |
| US-20070196442-A1 | Method for improving the oral administration of alpha-lipoic acid | MULTI FORMULATIONS LTD. (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2007044693-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | THE UNIVERSITY OF ALABAMA (US) | 2007-04-19 | — | — | WO | disclosed |