Lipoic Acid, Alpha

Lipoic Acid, Alpha

SCHEMBL51065

O=C(O)CCCCC1CCSS1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 1.00
KMT2A Q03164 2/20 1.00
TARDBP Q13148 2/20 1.00
CYP2C9 P11712 1/20 1.00
MEN1 O00255 1/20 1.00
NR1I2 O75469 1/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
POLB P06746 1/20 1.00
THRB P10828 1/20 1.00
TSHR P16473 1/20 1.00
ACHE P22303 1/20 1.00
APEX1 P27695 1/20 1.00
RECQL P46063 1/20 1.00
BLM P54132 1/20 1.00
PMP22 Q01453 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
SAE1 Q9UBE0 1/20 1.00
UBA2 Q9UBT2 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioctic Acid SCHEMBL4611014 1.00 HSD17B10 (1.00) HSD17B10KMT2ATARDBPCYP2C9MEN1
Lipoic Acid, Alpha SCHEMBL1981737 1.00 HSD17B10 (1.00) HSD17B10KMT2ATARDBPCYP2C9MEN1
Thioctic Acid SCHEMBL7924 1.00 HSD17B10 (1.00) HSD17B10KMT2ATARDBPCYP2C9MEN1
Lipoic Acid, Alpha SCHEMBL2128472 1.00 HSD17B10 (1.00) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL25257437 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1
Thioctic Acid SCHEMBL6037631 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1
Lipoic Acid, Alpha SCHEMBL6037633 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7914749 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1
Thioctic Acid SCHEMBL8948222 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1
Lipoic Acid, Alpha SCHEMBL4898905 0.98 HSD17B10 (0.96) HSD17B10KMT2ATARDBPCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22601 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121379932-B Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080099-A Amphiphilic nicotinamide adenine dinucleotide conjugate, nano micelle and application thereof 2026-05-26 CN claimed
CN-122080776-A Salt spray-resistant anti-aging cured coating and preparation method thereof 2026-05-26 CN claimed
WO-2026106919-A1 ENERGY BOOSTING AND MOBILITY INDUCING FORMULATION FOR ANIMALS INCLUDING PETS JONES MARGARET (US) 2026-05-21 WO claimed
US-20260137635-A1 NOVEL FORMULATIONS OF EPINEPHRINE AND USES THEREOF NANJING HAIWEI PHARMACEUTICAL TECH CO LTD (CN) 2026-05-21 US claimed
WO-2026106529-A1 NADP+-PRECURSOR AS ANTIAGING SUPPLEMENT DR CHARLES AB (SE) 2026-05-21 WO claimed
CN-122060038-A Anti-aging freeze-dried compound and preparation method and application thereof 海雅美生物技术(珠海)有限公司 2026-05-19 CN claimed
US-12630933-B2 Method for electrochemical preparation of polythioctic acid and derivative thereof JILIN UNIVERSITY (CN) 2026-05-19 US claimed
CN-122059654-A Composition for preparing cement-based composite material, preparation method and application thereof 中南大学 2026-05-19 CN claimed
CN-122031380-A Taqniamycin tartrate solution and preparation method thereof 正大康瑞(河南)生物科技有限公司 2026-05-15 CN claimed
CN-85101301-A The stable composition of interleukin II 1986-07-23 CN claimed
EP-0178665-A2 Stable erythropoietin preparation and process for formulating the same Chugai Seiyaku Kabushiki Kaisha (JP) 1986-04-23 EP claimed
EP-0158487-A2 Stable composition of interleukin-2 Takeda Chemical Industries, Ltd. (JP) 1985-10-16 EP claimed
US-4405648-A KNEADING WHEAT FLOUR, ASCORBIC ACID, REDUCING AGENTS AND THICKENERS, FERMENTATION, AND BAKING NISSHIN FLOUR MILLING CO., LTD. (JP) 1983-09-20 US claimed
EP-0080879-A2 Pharmaceutical composition containing interferon in stable state SUNSTAR KABUSHIKI KAISHA (JP) 1983-06-08 EP claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-4100150-A Stabilization of interferon against mechanical stress using thioctic acid G. D. SEARLE & CO. (US) 1978-07-11 US claimed
US-4054645-A TECHNETIUM ISOTOPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-10-18 US claimed
US-4031198-A PHARMACOLOGY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-06-21 US claimed