⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611710 | 1.00 | — | — | |
| SCHEMBL230054 | 1.00 | — | — | |
| SCHEMBL29034781 | 0.97 | — | — | |
| SCHEMBL31065523 | 0.80 | — | — | |
| SCHEMBL18074210 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL341632 | 0.78 | — | — | |
| SCHEMBL11182956 | 0.78 | — | — | |
| SCHEMBL291550 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL7752345 | 0.77 | — | — | |
| SCHEMBL790192 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409492-B1 | AN IMPROVED METHOD FOR PREPARATION OF CEFUROXIME AXETIL | LUPIN LTD (IN) | 2008-10-15 | — | — | EP | claimed |
| US-7064198-B2 | Method for preparation of cefuroxime axetil | LUPIN LIMITED (IN) | 2006-06-20 | — | — | US | claimed |
| US-6833452-B2 | Reacting an amine salt of cefuroxime with an esterifying agent | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-21 | — | — | US | claimed |
| US-20040077850-A1 | Method for preparation of cefuroxime axetil | LUPIN LIMITED (IN) | 2004-04-22 | — | — | US | claimed |
| EP-1303523-A1 | PROCESS FOR THE PREPARATION OF THE HIGHLY PURE CRYSTALLINE (R, S) - CEFUROXIME AXETIL | RANBAXY LABORATORIES, LTD. (IN) | 2003-04-23 | — | — | EP | claimed |
| US-20020016456-A1 | Process for the preparation of highly pure crystalline (R,S) - cefuroxime axetil | RANBAXY LABORATORIES LIMITED (IN) | 2002-02-07 | — | — | US | claimed |
| WO-2002006289-A1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE CRYSTALLINE (R,S) - CEFUROXIME AXETIL | RANBAXY LABORATORIES LIMITED (IN) | 2002-01-24 | — | — | WO | claimed |
| EP-1409492-B1 | AN IMPROVED METHOD FOR PREPARATION OF CEFUROXIME AXETIL | LUPIN LTD (IN) | 2008-10-15 | — | — | EP | disclosed |
| US-7064198-B2 | Method for preparation of cefuroxime axetil | LUPIN LIMITED (IN) | 2006-06-20 | — | — | US | disclosed |
| US-7064198-B2 | Method for preparation of cefuroxime axetil | LUPIN LIMITED (IN) | 2006-06-20 | — | — | US | disclosed |
| US-6833452-B2 | Reacting an amine salt of cefuroxime with an esterifying agent | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-21 | — | — | US | disclosed |
| US-20040077850-A1 | Method for preparation of cefuroxime axetil | LUPIN LIMITED (IN) | 2004-04-22 | — | — | US | disclosed |
| EP-1409492-A1 | AN IMPROVED METHOD FOR PREPARATION OF CEFUROXIME AXETIL | Lupin Limited (IN) | 2004-04-21 | — | — | EP | disclosed |
| US-5677443-A | HEATING IN WATER OR WATER MISCIBLE SOLVENT; COOLING; SEPARATION | ACS DOBFAR S.P.A. (IT) | 1997-10-14 | — | — | US | disclosed |
| EP-0757991-A1 | Bioavailable crystalline form of cefuroxime axetil | ACS DOBFAR S.p.A. (IT) | 1997-02-12 | — | — | EP | disclosed |
| EP-0338824-A2 | Esters of 6-beta-(alpha-oxyimino)-acylamino-penicillanic acid derivatives | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | disclosed |
| US-4816452-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-03-28 | — | — | US | disclosed |
| US-4385054-A | 1-Acetoxyethyl-3-(2-chloroethylcarbamoyloxymethyl)-7-[2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylate | GLAXO GROUP LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| US-4284766-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4258183-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |