⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822892 | 0.79 | — | — | |
| SCHEMBL230054 | 0.77 | — | — | |
| SCHEMBL4611078 | 0.77 | — | — | |
| SCHEMBL4611710 | 0.77 | — | — | |
| SCHEMBL427360 | 0.77 | — | — | |
| SCHEMBL29034781 | 0.74 | — | — | |
| SCHEMBL8901753 | 0.74 | TSHR (0.31) | — | |
| Trimethylammonium SCHEMBL10802051 | 0.74 | TSHR (0.42) | — | |
| SCHEMBL291550 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL9129538 | 0.72 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667346-A2 | Azole antifungal agents, process for the preparation there of and intermediates | Eisai Co., Ltd. (JP) | 1995-08-16 | — | — | EP | claimed |
| CN-122080417-A | Cast-in-place concrete hydration heat optimal control method for lock mass concrete structure | — | 2026-05-26 | — | — | CN | disclosed |
| CN-109071526-B | Acid addition salts of piperazine derivatives | 阿森纽荣股份公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-111138402-B | Preparation method of isocoumarin derivative | 苏州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-108218809-B | Synthetic method of medicine intermediate 2-aminothiazole-4-ethyl formate | 宁夏法安德药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-111138402-A | Preparation method of isocoumarin derivative | 苏州大学 | 2020-05-12 | — | — | CN | disclosed |
| US-10004730-B2 | Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-06-26 | — | — | US | disclosed |
| US-9981974-B2 | Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170246164-A1 | SMALL MOLECULES TARGETING ANDROGEN RECEPTOR NUCLEAR LOCALIZATION AND/OR LEVEL IN PROSTATE CANCER | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-08-31 | — | — | US | disclosed |
| US-20170247382-A1 | SMALL MOLECULES TARGETING ANDROGEN RECEPTOR NUCLEAR LOCALIZATION AND/OR LEVEL IN PROSTATE CANCER | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-08-31 | — | — | US | disclosed |
| EP-1250334-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-1242420-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1231210-A2 | Azole antifungal agents, processes for the preparation thereof, and intermediates | Eisai Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001044235-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001044247-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| CN-1226555-A | Antifungal agent, and preparation method and intermediate thereof | — | 1999-08-25 | — | — | CN | disclosed |
| US-5792781-A | EFFECTIVE AGAINST DERMATOMYCOSIS/VISCEROMYCOSIS CAUSED BY FUNGI, I.E., CANDIDA ALBICANS | EISAI CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5789429-A | FUNGICIDE | EISAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5648372-A | TRIAZOLES | EISAI CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0667346-A2 | Azole antifungal agents, process for the preparation there of and intermediates | Eisai Co., Ltd. (JP) | 1995-08-16 | — | — | EP | disclosed |