Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465777 | 0.91 | TSHR (0.46) | TSHRALDH1A1 | |
| SCHEMBL5492208 | 0.88 | — | — | |
| SCHEMBL9182398 | 0.83 | CTSK (0.36) | — | |
| SCHEMBL9184592 | 0.79 | CTSK (0.41) | TSHRALDH1A1NFKB1 | |
| SCHEMBL6564563 | 0.79 | — | — | |
| SCHEMBL4611710 | 0.78 | — | — | |
| SCHEMBL4611078 | 0.78 | — | — | |
| SCHEMBL230054 | 0.78 | — | — | |
| SCHEMBL291553 | 0.78 | — | — | |
| SCHEMBL11113675 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| EP-2727915-A1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | Concert Pharmaceuticals Inc. (US) | 2014-05-07 | — | — | EP | claimed |
| EP-4419513-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2025-08-27 | — | — | EP | disclosed |
| EP-4604951-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | AMIRA THERAPEUTICS, S.L. (ES) | 2025-08-27 | — | — | EP | disclosed |
| US-12384800-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2025-08-12 | — | — | US | disclosed |
| US-20250243174-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2025-07-31 | — | — | US | disclosed |
| WO-2025077996-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS | PHARMA MAR, S.A. (ES) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025050647-A1 | IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 晟迪生物医药(苏州)有限公司 | 2025-03-13 | — | — | WO | disclosed |
| US-12215100-B2 | Anticancer compounds | PHARMA MAR, S.A. (ES) | 2025-02-04 | — | — | US | disclosed |
| CN-110621678-B | Antitumor compounds | 法马马有限公司 | 2024-09-20 | — | — | CN | disclosed |
| EP-4419513-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2024-08-28 | — | — | EP | disclosed |
| WO-2009017671-A1 | SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2007144423-A1 | ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS | PHARMA MAR, S.A. (ES) | 2007-12-21 | — | — | WO | disclosed |
| US-5622944-A | MODIFIED 17-HYDROXY STEROL; TRANSDERMAL ELECTROTRANSPORT ENHANCEMENT | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-04-22 | — | — | US | disclosed |
| US-5202454-A | Catalytically reacting alpha-chlorinated carbonate derivatives with anhydrous brominated compound | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1993-04-13 | — | — | US | disclosed |
| US-4889929-A | ESTERIFICATION OF BENZYL PENICILLIN OR SALT WITH 1-BROMOETHYL ETHYL CARBONATE | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1989-12-26 | — | — | US | disclosed |
| EP-0108547-B1 | PROCESS FOR THE PREPARATION OF THE 1'-ETHOXYCARBONYLOXYETHYL ESTER OF BENZYLPENICILLIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1989-06-07 | — | — | EP | disclosed |
| US-4808745-A | Process for the preparation of 1-bromoethyl hydrocarbonyl carbonates and new 1-bromoethyl hydrocarbonyl carbonates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-02-28 | — | — | US | disclosed |
| US-4697032-A | Process for the preparation of 1-bromoethyl hydrocarbonyl carbonates and new 1-bromoethyl hydrocarbonyl carbonates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1987-09-29 | — | — | US | disclosed |
| EP-0108547-A2 | Process for the preparation of the 1'-ethoxycarbonyloxyethyl ester of benzylpenicillin | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1984-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384800-B2 | Antitumoral compounds | TP53, TOP1, MCL1 | TSHR 4670/4885ALDH1A1 144/4885THRB 4578/4885 |
| US-20250243174-A1 | ANTITUMORAL COMPOUNDS | MCL1, XPOT, GZMB | TSHR 3614/4885ALDH1A1 318/4885THRB 4496/4885 |
| US-12215100-B2 | Anticancer compounds | TP53, MCL1, MYC | TSHR 4635/4885ALDH1A1 795/4885THRB 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.