Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435938 | 0.86 | METAP2 (0.58) | METAP2 | |
| SCHEMBL13832796 | 0.86 | METAP2 (0.58) | METAP2 | |
| SCHEMBL10283996 | 0.85 | METAP2 (0.57) | METAP2 | |
| SCHEMBL435707 | 0.85 | METAP2 (0.57) | METAP2 | |
| SCHEMBL435166 | 0.82 | METAP2 (0.53) | METAP2KCNH2 | |
| SCHEMBL460088 | 0.80 | METAP2 (0.57) | METAP2KCNH2 | |
| SCHEMBL460087 | 0.80 | METAP2 (0.57) | METAP2KCNH2 | |
| SCHEMBL14947931 | 0.79 | METAP2 (0.45) | METAP2 | |
| SCHEMBL438059 | 0.79 | METAP2 (0.45) | METAP2 | |
| SCHEMBL14937362 | 0.79 | METAP2 (0.45) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595988-A1 | TRICYCLIC COMPOUNDS AND METHDS OF MAKING AND USING SAME | Zafgen, Inc. (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012642-A1 | TRICYCLIC COMPOUNDS AND METHDS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2012-01-26 | — | — | WO | disclosed |